LOC143506 Inhibitors
LOC143506 inhibitors, as a theoretical chemical class, could encompass a diverse range of compounds that indirectly influence the activity of this protein through various signaling pathways or cellular processes. These inhibitors are not known to target LOC143506 directly but are proposed to alter its functional state by modulating the activity of proteins and enzymes that interact with or regulate LOC143506.
The inhibitors listed, such as Staurosporine and LY294002, are thought to exert their effects by interfering with kinase activities and phosphoinositide 3-kinase (PI3K) pathways, respectively. Kinase inhibitors like Staurosporine may prevent the necessary phosphorylation events required for LOC143506 activation, while PI3K pathway inhibitors such as LY294002 and Wortmannin could disrupt critical signaling events necessary for LOC143506's localization or activation within the cell. Upstream inhibitors such as U0126, PD98059, and SB203580 can inhibit the MAPK pathway at different points-MEK and p38 MAPK, respectively-potentially reducing the activity of LOC143506 if it depends on MAPK-mediated signaling for its function.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A non-selective protein kinase inhibitor that could inhibit kinases that phosphorylate LOC143506, potentially preventing its activation or function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor that would reduce the production of PIP3, a secondary messenger that may be required for LOC143506's localization or activation. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
An inhibitor of MEK, which is upstream of ERK in the MAPK pathway. If LOC143506 is regulated by ERK-mediated signaling, U0126 could reduce its activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can downregulate protein synthesis and could decrease the functional protein levels of LOC143506 if it is mTOR-dependent. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
Another MEK inhibitor that prevents the activation of MAPK/ERK, potentially decreasing the activity of LOC143506 if it relies on this pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A p38 MAPK inhibitor, which could inhibit the function of LOC143506 if p38 MAPK is necessary for its activation or stability. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
A JNK inhibitor that could prevent the activation of LOC143506 if JNK signaling is involved in its regulatory mechanism. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
A PI3K inhibitor similar to LY294002, which could also disrupt PIP3-dependent processes affecting LOC143506. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $104.00 $141.00 | 14 | |
An AKT inhibitor that could decrease the phosphorylation and subsequent activation of LOC143506 if AKT is part of its regulation. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
A proteasome inhibitor that could increase the degradation of misfolded or damaged LOC143506 proteins, reducing its functional pool. | ||||||