LOC100041451 Inhibitors
Some nhibitors of LOC100041451 inhibitors could be Staurosporine which is a broad-spectrum kinase inhibitor that can suppress the phosphorylation-dependent signaling events, possibly regulating the activity or stability of LOC100041451. Similarly, Cyclopamine acts upon the Hedgehog pathway, a critical signaling cascade for cellular differentiation and proliferation. By inhibiting this pathway, Cyclopamine can impact the function of proteins associated with it, including LOC100041451.
Compounds such as 2-Methoxyestradiol and Thapsigargin target processes like angiogenesis and calcium homeostasis, respectively. These cellular processes are essential for maintaining the physiological environment in which proteins like LOC100041451 operate. By altering these environments, these inhibitors can modulate the function or expression of LOC100041451 indirectly. Other inhibitors in this class, like LY294002 and PD98059, specifically target key signaling nodes such as PI3K/AKT/mTOR and MAPK/ERK pathways. These pathways are ubiquitous in cellular signaling and can impact a multitude of proteins and cellular functions. By inhibiting these pathways, LY294002 and PD98059 can affect the downstream effects that might involve LOC100041451.
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that can suppress the activity of a wide range of kinases, potentially affecting the signaling pathways involving LOC100041451. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
A steroidal alkaloid that can inhibit the Hedgehog signaling pathway, which may intersect with the pathways regulated by LOC100041451. | ||||||
2-Methoxyestradiol | 362-07-2 | sc-201371 sc-201371A | 10 mg 50 mg | $70.00 $282.00 | 6 | |
A metabolite of estradiol that can inhibit angiogenesis and microtubule function, impacting the cellular environment of LOC100041451. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A MEK inhibitor that can prevent the activation of the MAPK/ERK pathway, potentially affecting processes that LOC100041451 is involved in. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that can disrupt the PI3K/AKT/mTOR pathway, which may be related to the function of LOC100041451. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
A SERCA pump inhibitor that can lead to increased cytosolic calcium levels, influencing signaling pathways where LOC100041451 may play a role. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
An Aurora kinase inhibitor that can disrupt cell division, potentially affecting the cell cycle regulation associated with LOC100041451. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor that can affect cytoskeleton organization and cell motility, processes that LOC100041451 might influence. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
A V-ATPase inhibitor that can disrupt lysosomal acidification, which may impact degradation pathways involving LOC100041451. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor that can prevent protein degradation, potentially influencing the turnover of LOC100041451 or its regulatory proteins. | ||||||