LOC100041358 Inhibitors
LOC100041358 inhibitors operate by targeting the upstream components that trigger the activation or expression of LOC100041358. For instance, Wortmannin and Triciribine specifically target the phosphoinositide 3-kinase (PI3K) and Akt signaling pathways, which are critical for controlling a broad array of cellular functions, including those associated with LOC100041358. Similarly, Selumetinib and Sorafenib inhibit the MAPK/ERK pathway and various tyrosine kinases respectively, suggesting that LOC100041358 may function within these pathways or be regulated by them.
Other inhibitors such as Go6976, Chelerythrine, and LY333531 focus on protein kinase C (PKC) isoforms, which play a pivotal role in signal transduction for a multitude of cellular processes. PD173074 and SU5402 target the fibroblast growth factor receptor (FGFR), indicative of LOC100041358's potential involvement in cell growth and differentiation pathways. AZD0530's action upon Src family kinases, and Lapatinib's inhibition of HER2 and EGFR, suggest a possible role for LOC100041358 in cellular proliferation and survival signaling networks. Roscovitine provides a means to interfere with the cell cycle through CDK inhibition, which can be pivotal if LOC100041358 is implicated in cell division control.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Inhibits PI3K, which can disrupt downstream signaling potentially controlling LOC100041358 activity. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $102.00 $138.00 | 14 | |
Inhibits Akt, which can suppress its downstream effects that may be necessary for LOC100041358 function. | ||||||
Selumetinib | 606143-52-6 | sc-364613 sc-364613A sc-364613B sc-364613C sc-364613D | 5 mg 10 mg 100 mg 500 mg 1 g | $28.00 $80.00 $412.00 $1860.00 $2962.00 | 5 | |
Inhibits MEK, which can prevent the activation of the MAPK/ERK pathway, potentially affecting LOC100041358 activity. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
Inhibits multiple tyrosine kinases, which can disrupt various signaling pathways that may regulate LOC100041358. | ||||||
Gö 6976 | 136194-77-9 | sc-221684 | 500 µg | $223.00 | 8 | |
Inhibits classical PKCs, which can alter signaling pathways that LOC100041358 may be part of. | ||||||
Chelerythrine chloride | 3895-92-9 | sc-3547 sc-3547A | 5 mg 25 mg | $88.00 $311.00 | 17 | |
Inhibits PKC, which can change the phosphorylation status and activity of proteins in pathways involving LOC100041358. | ||||||
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $46.00 $140.00 $680.00 | 16 | |
Inhibits FGFR, which can impact growth factor signaling pathways that might interact with LOC100041358. | ||||||
SU 5402 | 215543-92-3 | sc-204308 sc-204308A | 1 mg 5 mg | $62.00 $96.00 | 36 | |
Inhibits FGF receptors, which can alter the signaling cascades that may control LOC100041358 function. | ||||||
LY-333,531 Hydrochloride | 169939-93-9 | sc-364215 sc-364215A | 1 mg 5 mg | $92.00 $281.00 | 6 | |
Inhibits PKCβ, which can affect pathways that LOC100041358 may be involved in, particularly in vascular-related processes. | ||||||
Saracatinib | 379231-04-6 | sc-364607 sc-364607A | 10 mg 200 mg | $113.00 $1035.00 | 7 | |
Inhibits Src family kinases, which can affect signaling pathways that could regulate LOC100041358. | ||||||