The chemical class known as LOC100041273 Activators, also referred to by the alternative designation NADH:ubiquinone oxidoreductase subunit B4C activators, encompasses a group of specialized compounds designed to target and modulate the activity of the LOC100041273 gene. This gene encodes a subunit of the enzyme NADH:ubiquinone oxidoreductase, which is a critical component of the mitochondrial respiratory chain involved in the process of oxidative phosphorylation. The activators within this class are characterized by their ability to influence the expression and functionality of LOC100041273, thereby impacting the enzyme's role in cellular energy metabolism. The interaction between these activators and the LOC100041273 gene involves intricate molecular dynamics, potentially including direct binding to the gene or its regulatory elements, modulation of transcription and translation processes, or altering the post-translational modifications of the enzyme subunit, leading to enhanced or modified enzymatic activity.
Exploring the impact and mechanisms of action of LOC100041273 activators requires a comprehensive grasp of mitochondrial biology and the complex processes governing cellular energy production. By modulating the activity of LOC100041273, these activators can have significant implications for the efficiency and regulation of mitochondrial oxidative phosphorylation, potentially affecting ATP synthesis and the overall energy homeostasis within cells. This modulation is crucial for understanding the role of LOC100041273 in mitochondrial function, energy metabolism, and the cellular response to metabolic demands. The study of LOC100041273 activators thus provides valuable insights into the regulatory mechanisms of mitochondrial energy production, highlighting the intricate interplay between genetic regulation, enzymatic activity, and cellular energy dynamics, contributing to a deeper understanding of the fundamental processes that underpin cellular and organismal metabolism.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $71.00 $184.00 | 1 | |
Coenzyme Q10 is involved in the electron transport chain and might increase the demand for associated proteins. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $110.00 $150.00 $220.00 $300.00 $600.00 | 4 | |
NMN is a precursor of NAD+, which might stimulate the synthesis of NADH dehydrogenase subunits to maintain NADH/NAD+ balance. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
Alpha-lipoic acid is an antioxidant that may influence mitochondrial function and potentially upregulate related genes. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol has been shown to activate SIRT1, which might influence mitochondrial biogenesis and related genes. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Metformin can activate AMPK, which may affect mitochondrial function and biogenesis, potentially upregulating associated genes. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane activates Nrf2, which may induce antioxidant response element-mediated gene expression, including mitochondrial genes. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine activates AMPK and might influence mitochondrial function and the expression of related genes. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $57.00 $607.00 $176.00 | ||
Spermidine has been linked to autophagy and might influence mitochondrial turnover, which could affect expression of mitochondrial genes. | ||||||
Pterostilbene, Pterocarpus marsupium | 537-42-8 | sc-203223 sc-203223A | 10 mg 100 mg | $211.00 $1196.00 | ||
Pterostilbene, similar to resveratrol, is thought to activate sirtuins, potentially affecting genes related to mitochondrial function. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
NAC is a precursor to glutathione, an antioxidant that might influence mitochondrial protection and gene expression. | ||||||