The chemical class known as LOC100041107 Inhibitors encompasses a range of compounds specifically formulated to inhibit the activity of the gene product expressed by LOC100041107. This gene, identified through comprehensive genetic and molecular studies, has been recognized for its role in various cellular processes and functions. The functionality of LOC100041107 is highly context-dependent, meaning that its role can significantly vary based on the specific cellular environment and external stimuli. Inhibitors targeting LOC100041107 are developed with precision, aiming to selectively bind to the proteins or enzymes that are produced as a result of the gene's expression. This targeted binding is crucial as it directly impacts the biochemical pathways involving the LOC100041107 gene product. By modulating the activity of this gene product, these inhibitors are intended to influence the associated cellular processes, thereby impacting specific cellular functions and mechanisms.
The development of LOC100041107 Inhibitors is an intricate and multifaceted task that involves a blend of molecular biology, chemistry, and bioinformatics. The process begins with an in-depth understanding of the structure and function of the LOC100041107 gene product. Techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and computational molecular modeling are employed to gain a detailed insight into the target molecule. This foundational knowledge is essential for the rational design of inhibitors that are both effective in their interaction with the target and exhibit a high degree of specificity. Typically, these inhibitors are small molecules, crafted for efficient penetration into cellular membranes and establishing a stable and potent interaction with their target. The molecular design of these inhibitors is carefully optimized to ensure robust interactions with the target molecule, often involving hydrogen bonds, hydrophobic interactions, and van der Waals forces. The efficacy of these inhibitors is evaluated through various biochemical assays in vitro. These assays are crucial for assessing the inhibitors' potency, specificity, and overall behavior under controlled experimental conditions. This research is vital for understanding the inhibitors' mechanism of action and for further exploration into their potential impact on the complex network of cellular pathways influenced by LOC100041107.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide is known to inhibit transcription by affecting the activity of RNA polymerase II, potentially reducing gene expression. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol inhibits cyclin-dependent kinases, which can lead to the inhibition of transcription and decrease in gene expression. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB inhibits RNA polymerase II and can impede transcription elongation, potentially reducing gene expression. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $115.00 $337.00 | 3 | |
Betulinic acid can induce DNA damage response and modulate transcription factors, potentially affecting gene expression. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
JQ1 inhibits BET bromodomains, which can result in altered chromatin structure and changes in gene expression. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG-132 inhibits proteasomes, potentially leading to altered protein degradation and transcription factor activity. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
SAHA is a histone deacetylase inhibitor, influencing chromatin structure and gene expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin A binds to DNA and interferes with the binding of transcription factors, which can inhibit transcription. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA and impedes RNA polymerase, thus inhibiting transcription initiation and elongation. | ||||||
Oxamflatin | 151720-43-3 | sc-205960 sc-205960A | 1 mg 5 mg | $148.00 $461.00 | 4 | |
Oxamflatin is a histone deacetylase inhibitor, which can alter gene expression patterns by changing chromatin structure. | ||||||