The chemical class referred to as LOC100040500 Inhibitors represents a specific category of compounds designed to target and inhibit the activity of the gene product expressed by LOC100040500. This gene, identified through extensive genetic and molecular studies, is known to play a pivotal role in various cellular functions and processes. The exact role of LOC100040500 is highly dependent on the cellular context, with its function varying in response to different environmental conditions and stimuli. The inhibitors targeting this gene are specifically engineered for their ability to selectively bind to the proteins or enzymes that are produced as a result of LOC100040500 expression. The primary mechanism of these inhibitors involves the modulation of the biochemical pathways in which the LOC100040500 gene product is involved. By inhibiting the activity of this gene product, these compounds aim to affect the associated cellular processes and functions.
The development of LOC100040500 Inhibitors is a complex and interdisciplinary undertaking, involving molecular biology, chemistry, and bioinformatics. A thorough understanding of the structure and functional dynamics of the LOC100040500 gene product is crucial for the effective design of these inhibitors. Techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and computational molecular modeling are employed to gain in-depth insights into the target molecule. This comprehensive understanding allows for the rational design of inhibitors that are not only effective in their interaction but also exhibit high specificity for their target. These inhibitors are typically small molecules, optimized for efficient cellular penetration and stable interaction with their target. The molecular design of these inhibitors is carefully crafted to ensure strong hydrogen bonds, hydrophobic interactions, and van der Waals forces with the target molecule. The efficacy of these inhibitors is assessed through various in vitro biochemical assays. These assays are instrumental in evaluating the inhibitors' potency, specificity, and overall behavior in controlled experimental conditions. Such studies provide essential information about the inhibitors' mechanism of action and interaction dynamics, paving the way for further research into their influence on cellular pathways and functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Inhibits RNA polymerase II, thus potentially reducing the transcription of certain genes. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Binds to bacterial RNA polymerase, interfering with transcription initiation and potentially affecting gene expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Interferes with the elongation phase of transcription by binding to DNA, affecting RNA synthesis of multiple genes. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Affects transcription by modifying the activity of RNA polymerase II, which may alter gene expression patterns. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
Inhibits RNA polymerase II, and thus may impact the transcription of many genes. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Impedes transcription elongation by inhibiting positive transcription elongation factor b (P-TEFb). | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Analog of adenosine, can terminate mRNA chain elongation prematurely, potentially reducing gene expression. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $270.00 $465.00 $1607.00 $2448.00 $5239.00 | 4 | |
Blocks translation initiation, which might lead to a global reduction in protein synthesis from genes. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $51.00 $123.00 $178.00 | 11 | |
Inhibits translation initiation and thereby could decrease protein synthesis from multiple genes. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Inhibits peptide bond formation within ribosomes, affecting protein synthesis of many genes. | ||||||