Date published: 2025-11-1

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LOC100040500 Inhibitors

The chemical class referred to as LOC100040500 Inhibitors represents a specific category of compounds designed to target and inhibit the activity of the gene product expressed by LOC100040500. This gene, identified through extensive genetic and molecular studies, is known to play a pivotal role in various cellular functions and processes. The exact role of LOC100040500 is highly dependent on the cellular context, with its function varying in response to different environmental conditions and stimuli. The inhibitors targeting this gene are specifically engineered for their ability to selectively bind to the proteins or enzymes that are produced as a result of LOC100040500 expression. The primary mechanism of these inhibitors involves the modulation of the biochemical pathways in which the LOC100040500 gene product is involved. By inhibiting the activity of this gene product, these compounds aim to affect the associated cellular processes and functions.

The development of LOC100040500 Inhibitors is a complex and interdisciplinary undertaking, involving molecular biology, chemistry, and bioinformatics. A thorough understanding of the structure and functional dynamics of the LOC100040500 gene product is crucial for the effective design of these inhibitors. Techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and computational molecular modeling are employed to gain in-depth insights into the target molecule. This comprehensive understanding allows for the rational design of inhibitors that are not only effective in their interaction but also exhibit high specificity for their target. These inhibitors are typically small molecules, optimized for efficient cellular penetration and stable interaction with their target. The molecular design of these inhibitors is carefully crafted to ensure strong hydrogen bonds, hydrophobic interactions, and van der Waals forces with the target molecule. The efficacy of these inhibitors is assessed through various in vitro biochemical assays. These assays are instrumental in evaluating the inhibitors' potency, specificity, and overall behavior in controlled experimental conditions. Such studies provide essential information about the inhibitors' mechanism of action and interaction dynamics, paving the way for further research into their influence on cellular pathways and functions.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

Inhibits RNA polymerase II, thus potentially reducing the transcription of certain genes.

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$95.00
$322.00
$663.00
$1438.00
6
(1)

Binds to bacterial RNA polymerase, interfering with transcription initiation and potentially affecting gene expression.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Interferes with the elongation phase of transcription by binding to DNA, affecting RNA synthesis of multiple genes.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

Affects transcription by modifying the activity of RNA polymerase II, which may alter gene expression patterns.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$42.00
$185.00
$310.00
$650.00
6
(1)

Inhibits RNA polymerase II, and thus may impact the transcription of many genes.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$254.00
41
(3)

Impedes transcription elongation by inhibiting positive transcription elongation factor b (P-TEFb).

Cordycepin

73-03-0sc-203902
10 mg
$99.00
5
(1)

Analog of adenosine, can terminate mRNA chain elongation prematurely, potentially reducing gene expression.

Rocaglamide

84573-16-0sc-203241
sc-203241A
sc-203241B
sc-203241C
sc-203241D
100 µg
1 mg
5 mg
10 mg
25 mg
$270.00
$465.00
$1607.00
$2448.00
$5239.00
4
(1)

Blocks translation initiation, which might lead to a global reduction in protein synthesis from genes.

Homoharringtonine

26833-87-4sc-202652
sc-202652A
sc-202652B
1 mg
5 mg
10 mg
$51.00
$123.00
$178.00
11
(1)

Inhibits translation initiation and thereby could decrease protein synthesis from multiple genes.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$97.00
$254.00
36
(2)

Inhibits peptide bond formation within ribosomes, affecting protein synthesis of many genes.