LIR-6 Inhibitors
LIR-6 inhibitors constitute a specialized chemical class designed to selectively target and modulate the function of Leucine-rich repeat immunoreceptor 6 (LIR-6). LIR-6, also known as the Leucine-rich repeat-containing G protein-coupled receptor 6 (LGR6), belongs to the leucine-rich repeat (LRR) family of receptors that play diverse roles in cellular signaling and recognition processes. LIR-6 likely possesses unique structural features and is implicated in cellular functions such as stem cell maintenance and tissue regeneration. The inhibitors developed for LIR-6 are intricately designed to interact with the specific molecular structure of this receptor, aiming to disrupt its normal interactions within the cellular environment and potentially influencing cellular signaling cascades.
The molecular architecture of LIR-6 inhibitors is meticulously crafted to engage specific binding sites on the receptor, inducing changes in its conformation and dynamics. This interaction holds the potential to impact the receptor's ability to recognize and transduce signals, thereby influencing cellular responses. In laboratory research, these inhibitors serve as indispensable tools, allowing scientists to explore the nuanced functions of LIR-6 in various cellular contexts. By manipulating the function of LIR-6, researchers aim to unravel the intricate mechanisms governing stem cell regulation, tissue homeostasis, and potential implications for cellular development. The study of LIR-6 inhibitors stands at the forefront of advancing our understanding of the intricate signaling networks within cells, contributing to the broader knowledge of cellular biology and potential avenues for further research.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Sirolimus forms a complex with FKBP12 and inhibits mTOR, which can downregulate protein synthesis and potentially gene expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
This is a PI3K inhibitor that may reduce the activity of downstream pathways such as AKT, potentially affecting protein expression. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
It acts as an inhibitor of MEK, which may reduce the activity of the MAPK/ERK pathway and affect gene expression. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
As an inhibitor of p38 MAPK, this compound may alter the cellular response to stress and inflammation, potentially affecting gene expression. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor, potentially affecting transcription factor activity and gene expression. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor like LY294002, wortmannin may suppress AKT signaling and consequently affect protein expression levels. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
An Aurora kinase inhibitor that could disrupt the cell cycle and potentially downregulate various gene expressions. | ||||||
Alsterpaullone | 237430-03-4 | sc-202453 sc-202453A | 1 mg 5 mg | $67.00 $306.00 | 2 | |
This compound is a cyclin-dependent kinase inhibitor and may affect cell cycle progression and gene expression. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
It is a broad-spectrum protein kinase C inhibitor, potentially affecting multiple signaling pathways and gene expression. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $94.00 $348.00 | 69 | |
Also known as Compound C, it inhibits AMPK and may have off-target effects on BMP signaling, influencing gene expression. | ||||||