Lad Activators
The Lad Activators encompass a diverse range of chemical compounds that enhance the functional activity of Lad by indirectly affecting the specific signaling pathways or biological processes it is involved in. Compounds such as Staurosporine, Rottlerin, and Okadaic Acid exert their effects through the regulation of protein kinases and phosphatases. By inhibiting these proteins, they alter the competition for binding sites or affect the phosphorylation status of proteins that interact with Lad, leading to its activation. This group of activators highlights the intricate network of kinase- and phosphatase-mediated signal transduction in which Lad is involved.
In addition to kinase and phosphatase regulators, other Lad Activators act by influencing the cellular structures or processes Lad is involved in. Compounds like Vinblastine and Nocodazole disrupt microtubule dynamics, a process vital for many of Lad's functions. Similarly, Brefeldin A and MβCD influence the vesicle trafficking and membrane fluidity, respectively, thereby indirectly enhancing Lad's activity. Finally, Forskolin and IBMX increase cAMP levels, a second messenger known to regulate processes Lad is involved in. These activators underscore Lad's roles in cellular structure organization and signal transduction.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a potent inhibitor of protein kinases, and can influence the phosphorylation status of proteins that interact with Lad, indirectly enhancing Lad activity. | ||||||
Rottlerin | 82-08-6 | sc-3550 sc-3550B sc-3550A sc-3550C sc-3550D sc-3550E | 10 mg 25 mg 50 mg 1 g 5 g 20 g | $84.00 $166.00 $302.00 $2091.00 $5212.00 $16657.00 | 51 | |
Rottlerin is a kinase inhibitor that can modulate the activity of kinases which phosphorylate proteins involved in the same pathways as Lad, indirectly leading to its activation. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Okadaic Acid is a potent inhibitor of protein phosphatases. This can alter the phosphorylation status of proteins that interact with Lad, leading to its indirect activation. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Vinblastine disrupts microtubule dynamics, a process Lad is involved in. This can indirectly enhance Lad's functional activity. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubule dynamics, indirectly influencing Lad's functional activity given its role in this process. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Brefeldin A disrupts the Golgi apparatus and affects vesicle trafficking, indirectly influencing Lad due to its involvement in this process. | ||||||
Methyl-β-cyclodextrin | 128446-36-6 | sc-215379A sc-215379 sc-215379C sc-215379B | 100 mg 1 g 10 g 5 g | $20.00 $48.00 $160.00 $82.00 | 19 | |
MβCD depletes cholesterol from the plasma membrane. Given Lad's role in membrane-related processes, this can indirectly enhance its activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin increases intracellular cAMP levels, which is known to regulate processes Lad is involved in, leading to its indirect activation. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX inhibits phosphodiesterase, leading to increased cAMP levels, which can indirectly enhance Lad activity due to its role in cAMP-regulated processes. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $49.00 $57.00 $187.00 | 142 | |
Sodium Orthovanadate inhibits tyrosine phosphatases, altering the phosphorylation status of proteins interacting with Lad, thus indirectly enhancing its activity. | ||||||