KRTAP9-4 Activators

Minoxidil, a well-known vasodilator, stimulates hair follicle growth by dilating blood vessels and improving nutrient flow, creating an environment that facilitates keratin synthesis. Retinoic Acid promotes skin cell turnover and differentiation, processes that are essential for keratin protein integration into hair follicles. Finasteride works by inhibiting the 5-alpha-reductase enzyme, thus altering the hormonal milieu and potentially modulating keratin gene expression. Spironolactone serves a similar function by blocking androgen receptors, which could also influence the hormonal regulation of keratin expression. Ketoconazole and Zinc Pyrithione, both possessing antifungal properties, contribute to scalp health, a factor that is intrinsically connected to the proper functioning of hair follicles and the associated keratin proteins.

Caffeine and Bimatoprost, each extending the anagen phase of the hair cycle, provide a longer duration for keratin proteins to be synthesized, which is essential for robust hair growth. Antioxidant effects are provided by Epigallocatechin Gallate, which protects follicle cells from oxidative stress, thereby supporting the cellular framework necessary for keratin protein production. Copper peptides engage in tissue repair and uphold the structural integrity of hair follicles, potentially leading to an enhanced synthesis of keratin proteins.