KRTAP9-1 Inhibitors is a chemical class that primarily consists of small molecules or compounds designed to interact with and modulate the activity of the KRTAP9-1 protein. KRTAP9-1, or Keratin-associated protein 9-1, is a member of the keratin-associated protein family, which plays a crucial role in hair formation and maintenance. These inhibitors are meticulously crafted to interfere with the normal functioning of KRTAP9-1 through various molecular mechanisms. The goal of developing KRTAP9-1 inhibitors is to gain a deeper understanding of the intricate regulatory processes involved in hair growth and to explore potential applications in fields like cosmetics, hair care, and research.
The development of KRTAP9-1 inhibitors involves a meticulous process of identifying compounds that can selectively target KRTAP9-1 without affecting other proteins or biological pathways. These inhibitors may work through mechanisms such as competitive binding, allosteric modulation, or interference with post-translational modifications. By effectively inhibiting KRTAP9-1, researchers aim to elucidate the protein's role in hair biology and explore its potential relevance in improving hair quality and appearance. The study of KRTAP9-1 inhibitors may yield valuable insights into the underlying biology of hair growth and could pave the way for innovative approaches in the field of hair science and cosmetology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This compound is a DNA methyltransferase inhibitor that reduces DNA methylation, potentially affecting gene expression patterns including those related to KRTAP9-1. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
TSA is a histone deacetylase inhibitor, altering chromatin structure and potentially affecting transcription of various genes, including possibly KRTAP9-1. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic acid is another histone deacetylase inhibitor that can alter gene expression broadly by affecting chromatin remodeling. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
This compound binds to GC-rich sequences in DNA, potentially blocking transcription factors and affecting the expression of a range of genes. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine can raise endosomal pH and broadly affect cellular processes, potentially disrupting transcription factors or signaling pathways involved in gene expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, inhibiting RNA polymerase and thus broadly affecting RNA synthesis, including that of KRTAP9-1. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
This compound binds to bacterial RNA polymerase but may also affect eukaryotic cells by inhibiting RNA synthesis non-specifically. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin inhibits RNA polymerase II, a key enzyme in the transcription of DNA into mRNA, which could lead to a decrease in the expression of many genes, including KRTAP9-1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Sirolimus inhibits mTOR, which can affect protein synthesis and cellular growth processes, potentially leading to broad effects on gene expression. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
This glucose analog interferes with glycolysis and could lead to changes in cellular metabolism that broadly affect gene expression. | ||||||