KRTAP9-1 Activators
Keratin Associated Protein 9-1 (KRTAP9-1) belongs to the Keratin Associated Protein (KRTAP) family, a group of proteins crucial for the structure and mechanical properties of hair. The KRTAPs are known for their role in forming a protective matrix around hair keratins, contributing significantly to the strength, elasticity, and overall texture of hair fibers. KRTAP9-1, like other members of this family, interacts closely with the keratin filaments in hair, playing a key part in determining the physical qualities of hair. These proteins are often characterized by a high content of specific amino acids, such as cysteine, which are instrumental in forming strong disulfide bonds. These bonds are essential for the robustness and resilience of the hair fiber structure.
Activators of KRTAP9-1 would be chemical entities designed to enhance the function, expression, or stability of KRTAP9-1 within the hair shaft. Such activators could function through various mechanisms. One potential mechanism is the upregulation of KRTAP9-1 gene expression in hair follicle cells, which would increase the abundance of this protein in the hair matrix. Alternatively, activators might work by stabilizing the protein structure of KRTAP9-1 or by enhancing its interaction with keratin, thus reinforcing the hair's structural integrity. This could involve mechanisms that promote disulfide bond formation between cysteine residues in KRTAP9-1, a critical factor for its role in hair structure.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $45.00 | 5 | |
Ascorbic acid, or vitamin C, is essential for collagen synthesis and could influence the matrix around hair follicles, potentially affecting KRTAP9-1 expression. | ||||||
α-Linolenic Acid | 463-40-1 | sc-205545 sc-205545A | 50 mg 250 mg | $37.00 $113.00 | 2 | |
Alpha-linolenic acid, an omega-3 fatty acid, may affect inflammatory responses and thus indirectly influence KRTAP9-1 expression in hair follicles. | ||||||
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $36.00 $102.00 $569.00 $1173.00 | 10 | |
Oleic acid, a monounsaturated fatty acid, might modulate cellular membranes and signaling pathways related to hair follicle health and KRTAP9-1 expression. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $57.00 $93.00 $240.00 $713.00 | 8 | |
Found in pomegranates and berries, ellagic acid may influence cell proliferation and differentiation, potentially affecting KRTAP9-1 expression. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
Folic acid is vital for DNA synthesis and cell division, which are crucial processes in hair follicle activity that might impact KRTAP9-1 expression. | ||||||
Lycopene | 502-65-8 | sc-205738 sc-205738A sc-205738B | 1 mg 5 mg 1 g | $143.00 $571.00 $6125.00 | 4 | |
Lycopene, a phytochemical found in tomatoes, is an antioxidant that could modulate signaling pathways involving keratin and related proteins. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Nicotinamide, a form of vitamin B3, plays a role in energy metabolism and could be involved in the regulation of hair protein expression including KRTAP9-1. | ||||||
DL-α-Tocopherol | 10191-41-0 | sc-294383 sc-294383A sc-294383B sc-294383C | 5 g 25 g 100 g 500 g | $25.00 $51.00 $122.00 $320.00 | 3 | |
Tocopherol, or vitamin E, is an antioxidant that protects cells from oxidative stress, which could impact the expression of hair-related proteins. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc is important for protein synthesis and cell growth; its presence is critical for the maintenance of hair follicle health and could influence KRTAP9-1 expression. | ||||||
Linoleic Acid | 60-33-3 | sc-200788 sc-200788A sc-200788B sc-200788C | 100 mg 1 g 5 g 25 g | $33.00 $63.00 $163.00 $275.00 | 4 | |
Linoleic Acid is an essential fatty acid involved in the synthesis of ceramides, which are important for skin barrier function and may indirectly affect hair protein expression. | ||||||