KRTAP5-2 Activators
KRTAP5-2 utilize various biological pathways to enhance the function and expression of this hair-specific protein. Oleanolic Acid activates peroxisome proliferator-activated receptors, which can lead to the increased expression of KRTAP5-2 as part of the downstream effects of activated PPAR target genes. Similarly, Tretinoin and Retinoic Acid, both derivatives of Vitamin A, play a role in keratinocyte differentiation, which is crucial for the activation of hair keratin proteins. By promoting terminal differentiation in keratinocytes, these compounds foster an environment where KRTAP5-2 is highly expressed, thus enhancing its activity. Spermidine can initiate autophagy, a cellular process that might enhance the functionality of structural proteins like KRTAP5-2 within hair follicles by improving cellular turnover and maintenance.
Minoxidil, known for its role in hair follicle stimulation, opens potassium channels, which can increase the activity of KRTAP5-2 by enhancing the function of hair follicle cells. Copper Peptide (GHK-Cu) contributes to tissue remodeling and may enhance the activity of proteins involved in hair follicle development, including KRTAP5-2. The proliferation of dermal papilla cells is encouraged by Adenosine, which in turn elevates the activity of hair keratins such as KRTAP5-2. Caffeine extends the growth phase of hair follicle cells and by doing so, bolsters the activity of hair structural proteins, including KRTAP5-2. Pyrrolidinyl Diaminopyrimidine Oxide is associated with the enhancement of hair growth, which involves the activation of structural proteins like KRTAP5-2. Biotin, by improving the health and function of skin and hair cells, supports the expression of hair-specific keratin proteins such as KRTAP5-2. Lastly, Zinc, which is essential for protein synthesis and cell division, supports the activity of hair follicle proteins, such as KRTAP5-2, by facilitating keratinocyte proliferation where these structural proteins are utilized.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Oleanolic Acid | 508-02-1 | sc-205775 sc-205775A | 100 mg 500 mg | $86.00 $302.00 | 8 | |
Oleanolic Acid binds to and activates peroxisome proliferator-activated receptors (PPARs), which can lead to the activation of transcription factors that increase the expression of KRTAP5-2 as a downstream effect of PPAR target gene activation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Tretinoin, a derivative of Vitamin A, regulates keratinocyte differentiation and can promote the activation and function of hair keratin proteins including KRTAP5-2 by inducing terminal differentiation where these proteins are highly expressed. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $57.00 $607.00 $176.00 | ||
Spermidine has been shown to activate autophagy, a process that could enhance the turnover and function of structural proteins, including KRTAP5-2, in hair follicles, thereby potentially enhancing their structural role in hair shaft formation. | ||||||
Minoxidil (U-10858) | 38304-91-5 | sc-200984 sc-200984A | 100 mg 1 g | $69.00 $351.00 | ||
Minoxidil is known to open potassium channels and may enhance the function of hair follicle cells. This can lead to increased activity and presence of structural proteins like KRTAP5-2 in hair, contributing to hair growth and strength. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
Adenosine is known to increase the proliferation of dermal papilla cells and may enhance the activity of hair keratins like KRTAP5-2 by promoting an environment where hair growth is actively occurring. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine can stimulate hair follicle cells by extending their growth phase and may enhance the activity of hair structural proteins such as KRTAP5-2 by promoting keratinocyte activity. | ||||||
D-(+)-Biotin | 58-85-5 | sc-204706 sc-204706A sc-204706B | 1 g 5 g 25 g | $41.00 $107.00 $333.00 | 1 | |
Biotin is essential for the health of skin and hair cells and may promote the activity of hair-specific keratin proteins such as KRTAP5-2 by improving the overall health and function of cells where these proteins are expressed. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc plays a vital role in protein synthesis and cell division. Adequate levels of zinc could enhance the activity of hair follicle proteins such as KRTAP5-2 by supporting keratinocyte proliferation where these proteins are utilized. | ||||||