KRTAP16-7 Inhibitors
KRTAP16-7 inhibitors belong to a class of chemical compounds designed to selectively target and interfere with the activity of KRTAP16-7, a protein found within the Keratin-Associated Protein (KRTAP) family. These proteins are predominantly expressed in hair and hair follicles, where they play essential roles in shaping the structural and mechanical properties of hair fibers. KRTAP16-7, as a member of this family, is presumed to contribute to the structural integrity and functional characteristics of hair.
The primary mechanism of action for KRTAP16-7 inhibitors typically involves their interaction with the KRTAP16-7 protein or its associated molecules, leading to the modulation of its normal function. By inhibiting KRTAP16-7, these compounds have the ability to influence processes related to hair development, hair structure, or other cellular functions in which this protein is involved. However, the exact functions and molecular pathways associated with KRTAP16-7 are still subjects of active investigation. Scientists studying KRTAP16-7 inhibitors aim to uncover the precise roles and significance of KRTAP16-7 within the context of hair biology and other relevant cellular processes. These inhibitors serve as valuable tools for advancing our knowledge of KRTAP16-7 and its roles in cellular functions. In this context, they contribute to expanding our understanding of the complex interactions and functions of keratin-associated proteins in the biology of hair and related tissues.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sulfasalazine | 599-79-1 | sc-204312 sc-204312A sc-204312B sc-204312C | 1 g 2.5 g 5 g 10 g | $60.00 $75.00 $125.00 $205.00 | 8 | |
Sulfasalazine can influence NF-κB activity, which could potentially downregulate gene expression through transcriptional regulation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate, a histone deacetylase inhibitor, can cause hyperacetylation of histones, affecting chromatin structure and gene expression. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Methotrexate affects folate metabolism and can alter nucleotide synthesis, potentially affecting gene expression and protein production. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine can alter DNA and RNA synthesis by intercalating into nucleic acids, possibly affecting gene transcription levels. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, inhibiting transcriptional elongation by RNA polymerase, which can suppress gene expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin A binds to DNA and selectively inhibits transcription of GC-rich sequences, which could affect gene expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin inhibits RNA polymerase II, effectively halting mRNA synthesis and thus can downregulate gene expression. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Rifampicin can inhibit bacterial RNA polymerase, and while it primarily targets bacteria, it may affect mitochondrial gene expression. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Camptothecin inhibits topoisomerase I, preventing DNA re-ligation and potentially downregulating gene transcription. | ||||||
Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $82.00 $300.00 $1082.00 | 30 | |
Aphidicolin selectively inhibits DNA polymerase α and δ, potentially affecting DNA replication and associated gene expression. | ||||||