Date published: 2026-2-14

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Klkb1 Activators

Klkb1 Activators, short for Kallikrein B1 Activators, represent a class of molecules that play a pivotal role in regulating the kallikrein-kinin system, a complex biochemical pathway involved in blood coagulation, inflammation, and blood pressure regulation. These activators are typically small molecules or peptides that interact with and stimulate the activity of the Klkb1 enzyme. Klkb1, also known as plasma kallikrein, is a serine protease that plays a crucial role in the cleavage of kininogens into bradykinin, a potent vasodilator, and proinflammatory mediator.

One key characteristic of Klkb1 Activators is their ability to modulate the kallikrein-kinin system, thereby influencing various physiological processes. These activators can enhance the enzymatic activity of Klkb1, leading to increased bradykinin production, which in turn can have a range of effects on the cardiovascular and immune systems. While the specific mechanisms through which Klkb1 Activators operate can vary, they generally act by binding to Klkb1 and inducing conformational changes that promote its proteolytic activity. Understanding the molecular mechanisms and structures of Klkb1 Activators is of interest in the field of biochemistry and molecular biology, as it can shed light on the intricate regulation of the kallikrein-kinin system. Further research in this area may provide insights into potential applications beyond the realm of therapy, such as in the development of diagnostic tools or as targets for basic scientific investigations into blood clotting and inflammation.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Indole-3-carbinol

700-06-1sc-202662
sc-202662A
sc-202662B
sc-202662C
sc-202662D
1 g
5 g
100 g
250 g
1 kg
$39.00
$61.00
$146.00
$312.00
$1032.00
5
(1)

Indole-3-carbinol can modulate estrogen receptor signaling, potentially influencing the transcription of estrogen-responsive genes like Klkb1.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Genistein, a phytoestrogen, may interact with estrogen receptors and can influence the expression of genes responsive to estrogen, such as Klkb1.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin may affect gene expression and has potential antioxidant properties that could influence signaling pathways and Klkb1 expression.

Caffeic Acid

331-39-5sc-200499
sc-200499A
1 g
5 g
$32.00
$62.00
1
(2)

Caffeic acid has been shown to modulate cellular pathways and gene expression, which may include genes like Klkb1.

Kaempferol

520-18-3sc-202679
sc-202679A
sc-202679B
25 mg
100 mg
1 g
$99.00
$216.00
$510.00
11
(1)

Kaempferol can interact with cellular signaling pathways, potentially leading to changes in gene expression, including Klkb1.

Ellagic Acid, Dihydrate

476-66-4sc-202598
sc-202598A
sc-202598B
sc-202598C
500 mg
5 g
25 g
100 g
$58.00
$95.00
$245.00
$727.00
8
(1)

Ellagic acid is known for its potential to modulate pathways of cellular protection and may influence Klkb1 gene expression.

Capsaicin

404-86-4sc-3577
sc-3577C
sc-3577D
sc-3577A
50 mg
250 mg
500 mg
1 g
$96.00
$160.00
$240.00
$405.00
26
(1)

Capsaicin activates certain cellular receptors and might influence signaling pathways that regulate genes like Klkb1.

Cinnamic Aldehyde

104-55-2sc-294033
sc-294033A
100 g
500 g
$104.00
$228.00
(0)

Cinnamaldehyde can modulate gene expression through its potential effects on cellular signaling pathways, which could include Klkb1.

Naringenin

480-41-1sc-219338
25 g
$245.00
11
(1)

Naringenin, a flavonoid, is known to modulate gene expression, which could potentially result in altered Klkb1 expression.

Gallotannin

1401-55-4sc-202619
sc-202619A
sc-202619B
sc-202619C
sc-202619D
sc-202619E
sc-202619F
1 g
10 g
100 g
250 g
1 kg
2.5 kg
5 kg
$26.00
$37.00
$67.00
$78.00
$234.00
$536.00
$983.00
12
(1)

Tannic acid may influence gene expression by interacting with proteins involved in transcription regulation, possibly affecting Klkb1.