Klkb1 inhibitors represent a class of chemical compounds designed to selectively target and interfere with the activity of Klkb1, also known as Kallikrein B1, a serine protease enzyme encoded by the Klkb1 gene. Klkb1 is a member of the kallikrein-related peptidase family, involved in various proteolytic processes and cascade reactions.These inhibitors are developed with the aim of modulating the function of Klkb1, which could be involved in a range of biological processes, including proteolysis, blood clotting, and other molecular activities within the body.
The primary mechanism of action for Klkb1 inhibitors typically involves their interaction with the Klkb1 protein or its associated molecules, leading to the disruption of its normal proteolytic function. By inhibiting Klkb1, these compounds have the ability to influence cellular processes where this enzyme plays a role, although the specific functions and substrates of Klkb1 are still the subject of ongoing research. Scientists studying Klkb1 inhibitors aim to elucidate the precise roles and functions of Klkb1 in cellular biology, contributing to our understanding of its significance within various physiological contexts. These inhibitors serve as valuable tools for advancing our knowledge of Klkb1 and its roles in proteolytic pathways and other cellular functions. In this context, they contribute to expanding our understanding of the intricate world of proteases and their impact on cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
A diterpene triepoxide that inhibits the transcription of various genes and could potentially suppress Klkb1 expression. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
A proteasome inhibitor that can affect the degradation of proteins involved in cell cycle and transcription regulation. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
A kinase inhibitor that targets multiple enzymes, potentially affecting signaling pathways that regulate gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An inhibitor of histone deacetylase, which could alter chromatin structure and gene expression patterns. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A nucleoside analog that incorporates into DNA and RNA, demethylates DNA, and can alter gene expression. | ||||||
Oxaliplatin | 61825-94-3 | sc-202270 sc-202270A | 5 mg 25 mg | $110.00 $386.00 | 8 | |
A platinum-based antineoplastic agent that forms DNA adducts, potentially affecting DNA replication and transcription. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
A DNA methyltransferase inhibitor that can lead to hypomethylation of DNA and subsequent changes in gene expression. | ||||||
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $126.00 $278.00 $984.00 | 3 | |
A cytidine analog that can be incorporated into DNA and inhibit DNA methyltransferase, potentially altering gene expression. | ||||||
Sodium phenylbutyrate | 1716-12-7 | sc-200652 sc-200652A sc-200652B sc-200652C sc-200652D | 1 g 10 g 100 g 1 kg 10 kg | $75.00 $163.00 $622.00 $4906.00 $32140.00 | 43 | |
An HDAC inhibitor that can change the acetylation status of histones, affecting gene expression including potentially Klkb1. | ||||||
Alsterpaullone | 237430-03-4 | sc-202453 sc-202453A | 1 mg 5 mg | $67.00 $306.00 | 2 | |
An inhibitor of cyclin-dependent kinases, which has been shown to affect cell cycle regulation and gene expression. | ||||||