KLHL4 Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Inhibits proteasomal degradation. By doing so, KLHL4's capacity to target proteins for degradation might be impeded as ubiquitinated proteins would accumulate. | ||||||
Lactacystin | 133343-34-7 | sc-3575 sc-3575A | 200 µg 1 mg | $188.00 $575.00 | 60 | |
A selective proteasome inhibitor that could prevent KLHL4 from fulfilling its role in targeting proteins for degradation. | ||||||
Epoxomicin | 134381-21-8 | sc-201298C sc-201298 sc-201298A sc-201298B | 50 µg 100 µg 250 µg 500 µg | $137.00 $219.00 $449.00 $506.00 | 19 | |
Specifically binds and inhibits the proteasome, which may cause KLHL4's substrates to accumulate, diminishing its functional efficiency. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Directly inhibits the 26S proteasome. As KLHL4 targets proteins for degradation, Bortezomib can impede this process by preventing proteasomal degradation. | ||||||
Celastrol, Celastrus scandens | 34157-83-0 | sc-202534 | 10 mg | $158.00 | 6 | |
Hinders proteasome activity; thus, it may indirectly affect KLHL4's capacity to effectively target proteins for proteasomal degradation. | ||||||
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | $96.00 $292.00 | 27 | |
Inhibits Wnt production. If KLHL4 interacts or is regulated by the Wnt pathway, this can suppress its normal functionality. | ||||||
IWR-1-endo | 1127442-82-3 | sc-295215 sc-295215A | 5 mg 10 mg | $82.00 $135.00 | 19 | |
A Wnt pathway inhibitor; its influence on KLHL4 can be an indirect suppression if KLHL4 is involved in Wnt-regulated processes. | ||||||
Neratinib | 698387-09-6 | sc-364549 sc-364549A sc-364549B sc-364549C sc-364549D | 5 mg 25 mg 100 mg 500 mg 1 g | $92.00 $214.00 $383.00 $755.00 $1250.00 | 4 | |
As a tyrosine kinase inhibitor, it can modulate KLHL4 if the protein has any tyrosine kinase-related functions or interactions. | ||||||
DBeQ | 177355-84-9 | sc-499943 | 10 mg | $330.00 | 1 | |
By inhibiting p97, it disrupts protein degradation. This can indirectly impede KLHL4's role in targeting specific proteins for degradation. | ||||||
Spautin-1 | 1262888-28-7 | sc-507306 | 10 mg | $168.00 | ||
It induces autophagy by inhibiting ubiquitin-specific peptidases. This action can increase the ubiquitination levels, which may overwhelm KLHL4's capacity to target them. | ||||||