KIR3DS1 Inhibitors
KIR3DS1 inhibitors belong to a specific class of chemical compounds designed to selectively modulate the activity of the killer cell immunoglobulin-like receptor 3DS1 (KIR3DS1) protein. KIR3DS1 is a member of the killer cell immunoglobulin-like receptor (KIR) family, predominantly expressed on natural killer (NK) cells, a subset of immune cells. While the functional role of KIR3DS1 is intricately linked to immune responses, the precise mechanisms and regulatory pathways governed by this receptor are still being elucidated. The inhibitors tailored for KIR3DS1 exhibit a specialized chemical structure that enables them to interact selectively with defined binding sites on the KIR3DS1 protein, influencing its molecular activities within the context of immune cell function.
The mechanism of action of KIR3DS1 inhibitors involves disrupting the normal functioning of the KIR3DS1 protein, potentially impacting immune responses and cellular interactions mediated by NK cells. The specific design of these inhibitors is crucial to ensure a high degree of selectivity, minimizing unintended effects on other immune receptors or cellular components. As researchers delve into the complexities of immune regulation and the role of KIR3DS1 in mediating immune responses, inhibitors targeting this receptor provide valuable tools for deciphering the precise molecular mechanisms controlled by KIR3DS1. The study of this chemical class contributes to a deeper understanding of the role played by KIR3DS1 in immune cell biology, offering insights into its potential functions within the intricate networks that regulate immune surveillance and response.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is known to modulate several signaling pathways which can affect the expression of various genes, potentially including immune-related genes like KIR3DS1. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein is an isoflavone that can act as a tyrosine kinase inhibitor, potentially altering signaling pathways and gene expression profiles relevant to immune function. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has been shown to affect transcription factors and signaling pathways, which may result in the downregulation of certain genes, including potentially KIR3DS1. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
As a histone deacetylase inhibitor, sodium butyrate can alter chromatin structure and thereby influence gene expression, which might include KIR3DS1. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid affects gene expression through its role as an active metabolite of vitamin A, involved in the regulation of immune system genes. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane is a compound found in cruciferous vegetables that can influence NF-κB pathway, potentially modulating immune-related gene expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, the major catechin in green tea, may downregulate the expression of genes involved in inflammation and immune response through various pathways. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $39.00 $61.00 $146.00 $312.00 $1032.00 | 5 | |
This compound, derived from cruciferous vegetables, is thought to modulate estrogen metabolism and may impact the expression of certain genes in immune cells. | ||||||
Allyl disulfide | 2179-57-9 | sc-252359 | 25 g | $80.00 | ||
Found in garlic, this organosulfur compound can affect the transcription of various genes, potentially influencing the expression of genes like KIR3DS1. | ||||||
Chlorogenic Acid | 327-97-9 | sc-204683 sc-204683A | 500 mg 1 g | $47.00 $69.00 | 1 | |
Chlorogenic acid is a polyphenol that may affect the expression of genes by modulating inflammation and oxidative stress-related pathways. | ||||||