KIAA1462 is a gene that encodes a protein less characterized in the scientific literature but has garnered interest due to its association with cardiovascular health, particularly coronary artery disease (CAD). The protein encoded by KIAA1462 is believed to be involved in cellular processes that are critical in vascular biology, such as cell adhesion, signaling, and interactions with the extracellular matrix.Studies have suggested that KIAA1462 may play a role in the development and progression of CAD. Its expression is often observed in endothelial cells, which line the interior surface of blood vessels. The endothelium plays a crucial role in maintaining vascular tone, blood flow, and the integrity of the vascular wall, making KIAA1462 significant in maintaining vascular health.
Additionally, KIAA1462 might be involved in the pathophysiological processes underlying atherosclerosis, a condition characterized by the buildup of plaques within arteries, leading to reduced blood flow and an increased risk of heart attack and stroke. This involvement is likely related to its functions in cell-cell interactions and signaling pathways that regulate vascular remodeling and inflammation, key factors in atherosclerosis development.Moreover, genetic studies have shown an association between polymorphisms in the KIAA1462 gene and increased risk of CAD, suggesting that variations in this gene could influence individual susceptibility to cardiovascular diseases.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $31.00 $89.00 $135.00 $443.00 | 13 | |
Statins may upregulate KIAA1462 as part of their role in modulating cholesterol levels and improving endothelial function. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin may modulate KIAA1462 expression through its anti-inflammatory effects on vascular tissues. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin might influence KIAA1462 due to its antioxidant activity and potential effects on endothelial cells. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
This compound, found in cruciferous vegetables, may affect KIAA1462 expression due to its detoxifying and antioxidant properties. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Catechins could regulate KIAA1462 expression in relation to their benefits for vascular health and endothelial function. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine might impact KIAA1462 expression through its physiological effects on the cardiovascular system. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine may influence KIAA1462 expression, potentially due to its role in metabolic regulation and vascular health. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $71.00 $184.00 | 1 | |
This compound could modulate KIAA1462 expression through its role in cellular energy processes and antioxidant defense. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
Nicotinamide might affect KIAA1462 expression due to its involvement in cellular metabolism and vascular function. | ||||||