KIAA0649 Activators
KIAA0649 activators are a diverse group of chemical compounds that can enhance the expression or activity of the KIAA0649 protein. They can be broadly classified into two main types: direct activators and indirect activators.
Direct activators of KIAA0649 interact directly with the protein and enhance its function. Examples of direct activators include detergents, reducing agents, alkylating agents, and crosslinking agents. Detergents disrupt cell membranes and expose the extracellular domain of KIAA0649 to its ligands. Reducing agents activate KIAA0649 by breaking disulfide bonds in the protein, exposing cryptic epitopes that can be recognized by antibodies or other ligands. Alkylating agents directly activate KIAA0649 by modifying cysteine residues in the protein, altering its structure and function. Crosslinking agents can activate KIAA0649 by crosslinking adjacent proteins in the cell membrane, stabilizing the protein in its active conformation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases intracellular cAMP, potentially activating cAMP-dependent protein kinase A (PKA) and influencing gene expression. | ||||||
Amlodipine | 88150-42-9 | sc-200195 sc-200195A | 100 mg 1 g | $73.00 $163.00 | 2 | |
Acts as a calcium channel blocker, increasing intracellular calcium and activating calcium-dependent signaling pathways. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Inhibits histone deacetylase (HDAC), altering chromatin structure and potentially increasing transcription of certain genes. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Inhibits DNA methyltransferase, reducing DNA methylation and potentially activating silenced genes. | ||||||
Vemurafenib | 918504-65-1 | sc-364643 sc-364643A | 10 mg 50 mg | $115.00 $415.00 | 11 | |
Inhibits BRAF kinase, impacting the MAPK/ERK signaling pathway and potentially affecting downstream gene expression. | ||||||
Clonidine | 4205-90-7 | sc-501519 | 100 mg | $235.00 | 1 | |
Acts as an agonist of alpha-2 adrenergic receptors, modulating G protein-coupled receptor signaling pathways. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Acts as an ionophore, altering intracellular ion concentrations and impacting various cellular processes. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
Modulates the activity of transcription factors like NF-κB, influencing gene expression related to inflammation. | ||||||
Prednisone | 53-03-2 | sc-205816 sc-205816A sc-205816B | 1 g 5 g 25 g | $41.00 $133.00 $663.00 | 2 | |
Activates glucocorticoid receptors, impacting genes involved in inflammatory and immune responses. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
Activates PPARγ, influencing lipid metabolism and gene expression related to insulin sensitivity. | ||||||