Date published: 2026-1-16

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KCTD6 Activators

KCTD6 Activators are a group of compounds that specifically target and modulate the activity or expression of the potassium channel tetramerization domain-containing protein 6 (KCTD6). By definition, these activators would engage with the KCTD6 protein or its regulatory elements to enhance its function or promote its gene expression. The mechanisms by which these activators operate could be highly diverse, reflecting the complexity of protein regulation within a cell. They may act directly upon the protein, altering its conformation to a more active state or facilitating its interaction with other molecular partners essential for its function. Alternatively, they could interact with the cellular machinery responsible for the gene expression of KCTD6, such as transcription factors or epigenetic modifiers, to increase its production levels.

The activators in this chemical class could encompass a range of molecular structures, from simple organic molecules to complex natural products. Their design would likely be influenced by detailed structural knowledge of KCTD6, employing techniques such as high-throughput screening, computational modeling, and medicinal chemistry to identify and optimize potential binding interactions. The study and characterization of KCTD6 Activators would involve an interdisciplinary approach, combining biochemistry, molecular biology, and chemistry to elucidate their mechanism of action at a molecular level. These activators would be of particular interest in research focused on elucidating the physiological roles of KCTD6, including its involvement in potassium ion channel regulation, and in broader cellular processes where KCTD6 plays a contributory role. The pursuit of understanding these activators would contribute significantly to the fundamental knowledge of cellular ion channel regulation and the intricate networks that control protein function.

SEE ALSO...

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA activates protein kinase C (PKC) which may initiate a signaling cascade affecting gene transcription, possibly including KCTD6.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG is known to modulate cellular pathways and could influence gene expression profiles, potentially affecting KCTD6.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium butyrate acts as an HDAC inhibitor, leading to chromatin remodeling and potentially altering KCTD6 gene expression.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin raises intracellular cAMP levels, which may modulate transcription factors and influence KCTD6 expression.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium affects several signaling pathways such as GSK-3 inhibition, possibly impacting gene expression including KCTD6.

Rosiglitazone

122320-73-4sc-202795
sc-202795A
sc-202795C
sc-202795D
sc-202795B
25 mg
100 mg
500 mg
1 g
5 g
$120.00
$326.00
$634.00
$947.00
$1259.00
38
(1)

As a PPARγ agonist, rosiglitazone may affect transcriptional regulation of genes involved in cellular signaling, like KCTD6.

Betulinic Acid

472-15-1sc-200132
sc-200132A
25 mg
100 mg
$117.00
$344.00
3
(1)

Betulinic acid can modulate signaling pathways and transcription factors, which may induce KCTD6 gene expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin is known to affect a wide range of signaling molecules and may alter the transcription of genes like KCTD6.

Adenosine 3′,5′-cyclic monophosphate

60-92-4sc-217584
sc-217584A
sc-217584B
sc-217584C
sc-217584D
sc-217584E
100 mg
250 mg
5 g
10 g
25 g
50 g
$116.00
$179.00
$265.00
$369.00
$629.00
$1150.00
(1)

Dibutyryl-cAMP, a cAMP analog, can activate PKA leading to changes in gene expression profiles including KCTD6.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid regulates gene expression via nuclear receptors, potentially affecting signaling pathways related to KCTD6.