KCTD6 Activators are a group of compounds that specifically target and modulate the activity or expression of the potassium channel tetramerization domain-containing protein 6 (KCTD6). By definition, these activators would engage with the KCTD6 protein or its regulatory elements to enhance its function or promote its gene expression. The mechanisms by which these activators operate could be highly diverse, reflecting the complexity of protein regulation within a cell. They may act directly upon the protein, altering its conformation to a more active state or facilitating its interaction with other molecular partners essential for its function. Alternatively, they could interact with the cellular machinery responsible for the gene expression of KCTD6, such as transcription factors or epigenetic modifiers, to increase its production levels.
The activators in this chemical class could encompass a range of molecular structures, from simple organic molecules to complex natural products. Their design would likely be influenced by detailed structural knowledge of KCTD6, employing techniques such as high-throughput screening, computational modeling, and medicinal chemistry to identify and optimize potential binding interactions. The study and characterization of KCTD6 Activators would involve an interdisciplinary approach, combining biochemistry, molecular biology, and chemistry to elucidate their mechanism of action at a molecular level. These activators would be of particular interest in research focused on elucidating the physiological roles of KCTD6, including its involvement in potassium ion channel regulation, and in broader cellular processes where KCTD6 plays a contributory role. The pursuit of understanding these activators would contribute significantly to the fundamental knowledge of cellular ion channel regulation and the intricate networks that control protein function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC) which may initiate a signaling cascade affecting gene transcription, possibly including KCTD6. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is known to modulate cellular pathways and could influence gene expression profiles, potentially affecting KCTD6. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate acts as an HDAC inhibitor, leading to chromatin remodeling and potentially altering KCTD6 gene expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin raises intracellular cAMP levels, which may modulate transcription factors and influence KCTD6 expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium affects several signaling pathways such as GSK-3 inhibition, possibly impacting gene expression including KCTD6. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
As a PPARγ agonist, rosiglitazone may affect transcriptional regulation of genes involved in cellular signaling, like KCTD6. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $117.00 $344.00 | 3 | |
Betulinic acid can modulate signaling pathways and transcription factors, which may induce KCTD6 gene expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is known to affect a wide range of signaling molecules and may alter the transcription of genes like KCTD6. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
Dibutyryl-cAMP, a cAMP analog, can activate PKA leading to changes in gene expression profiles including KCTD6. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid regulates gene expression via nuclear receptors, potentially affecting signaling pathways related to KCTD6. | ||||||