KCTD19 inhibitors constitute a class of chemical compounds specifically designed to target and interfere with the activity of the KCTD19 gene or its encoded protein product. KCTD19, short for Potassium Channel Tetramerization Domain-Containing 19, is a gene or protein that plays a role in cellular processes. These inhibitors are developed with the aim of modulating the function of KCTD19, which could be involved in various biological processes, such as ion channel regulation, protein-protein interactions, or other molecular activities within cells.
The primary mechanism of action for KCTD19 inhibitors typically involves their interaction with the KCTD19 protein or its associated molecules, leading to the disruption of its normal function. By inhibiting KCTD19, these compounds have the ability to impact cellular processes under its control, although the specific functions of KCTD19 are still being explored by researchers. Scientists studying KCTD19 inhibitors aim to elucidate the precise roles and functions of KCTD19 in cellular biology, contributing to our understanding of its significance within cellular processes. These inhibitors serve as valuable tools for advancing our knowledge of less-characterized genes or proteins, enabling the exploration of new areas of molecular and cellular biology research. In this context, they contribute to expanding our understanding of the intricate world of cellular functions and molecular interactions.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol inhibits cyclin-dependent kinases, which could alter cell cycle progression and potentially downregulate genes involved in cell division. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib inhibits the 26S proteasome, which could lead to increased cellular stress and potentially downregulate certain genes. | ||||||
MLN8237 | 1028486-01-2 | sc-394162 | 5 mg | $220.00 | ||
Alisertib inhibits Aurora A kinase, which may affect cell cycle progression and subsequently gene expression. | ||||||
Ibrutinib | 936563-96-1 | sc-483194 | 10 mg | $153.00 | 5 | |
Ibrutinib inhibits Bruton's tyrosine kinase, which could modulate B cell receptor signaling and influence gene expression. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
Thalidomide binds to the E3 ubiquitin ligase complex, which might result in the degradation of transcription factors and reduced gene expression. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide has been shown to inhibit the transcriptional activity of NF-κB, which could downregulate the expression of target genes. | ||||||
Salubrinal | 405060-95-9 | sc-202332 sc-202332A | 1 mg 5 mg | $33.00 $102.00 | 87 | |
Salubrinal is a selective inhibitor of eIF2α dephosphorylation, which could affect protein synthesis and gene expression. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Tunicamycin inhibits N-linked glycosylation, which could lead to ER stress and potentially downregulate protein expression. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $163.00 $316.00 | 436 | |
Puromycin causes premature chain termination during translation, which could decrease overall protein synthesis, including KCTD proteins. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $51.00 $123.00 $178.00 | 11 | |
Homoharringtonine inhibits the initial elongation step of protein synthesis, potentially reducing the expression of many proteins. |