KCTD14 Inhibitors
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A potent kinase inhibitor that can prevent phosphorylation events required for the recruitment or activation of KCTD14. If KCTD14 requires phosphorylation for its function, Staurosporine would impair its activity. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Disrupts protein trafficking by inhibiting the exchange factor for ARF1 GTPase, potentially affecting the endoplasmic reticulum-Golgi intermediate compartment where KCTD14 may be localized or reliant on for function. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Inhibits N-linked glycosylation in the ER, leading to ER stress and potential misfolding of proteins. If KCTD14 function depends on glycosylation, Tunicamycin would lead to its functional inhibition. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Inhibits the eukaryotic ribosomal translocation process, indirectly leading to decreased levels of proteins, including KCTD14, if it has a short half-life or rapid turnover. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
A proteasome inhibitor leading to the accumulation of polyubiquitinated proteins, potentially affecting proteins that regulate or interact with KCTD14, leading to its functional inhibition. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
A glycolysis inhibitor that can lead to energy depletion. If KCTD14 requires ATP for its function or stability, its activity would be inhibited in an energy-depleted environment. | ||||||
MLN8237 | 1028486-01-2 | sc-394162 | 5 mg | $220.00 | ||
An Aurora A kinase inhibitor, which could disrupt mitotic events. If KCTD14 is involved in cell cycle regulation, particularly mitosis, its function would be inhibited by Alisertib. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
An inhibitor of SERCA pumps, elevating cytosolic Ca2+ and inducing ER stress, which can lead to the functional inhibition of KCTD14 if it is sensitive to calcium homeostasis or ER stress. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Increases intracellular calcium concentration, affecting proteins sensitive to Ca2+ levels. If KCTD14 activity is calcium-dependent, Ionomycin could inhibit its function. | ||||||
W-7 | 61714-27-0 | sc-201501 sc-201501A sc-201501B | 50 mg 100 mg 1 g | $166.00 $306.00 $1675.00 | 18 | |
A calmodulin antagonist that can inhibit calcium-calmodulin-dependent processes. If KCTD14 interacts with calmodulin or is regulated by it, W7 Hydrochloride would inhibit KCTD14 activity. | ||||||