Potassium channel regulator (KCNRG) is a protein that in humans is encoded by the KCNRG gene. As the name suggests, it is involved in the regulation of potassium channels, which are key players in numerous cellular functions.Potassium channels are protein complexes that allow the passage of potassium ions across cell membranes. They contribute to a variety of processes, including the regulation of cell membrane potential, signal transduction, and the control of cell volume.Its regulatory function could potentially influence a variety of cellular processes through its impact on potassium channel activity.
The KCNRG gene is also of interest in the context of lung diseases. Some studies have found that variations in the KCNRG gene are associated with susceptibility to tuberculosis and chronic obstructive pulmonary disease (COPD). It has also been suggested that KCNRG might play a role in bronchial responsiveness, a trait related to asthma.Additionally, some research has pointed to a potential role for KCNRG in cancer. For instance, KCNRG has been found to be downregulated in certain types of leukemia, suggesting that it may act as a tumor suppressor in some contexts.Further research on KCNRG is needed to better understand its specific roles in potassium channel regulation and its potential implications for human health and disease
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Amiodarone | 1951-25-3 | sc-480089 | 5 g | $318.00 | ||
Amiodarone affects various potassium channels and could indirectly influence KCNRG's regulatory function. | ||||||
Apamin | 24345-16-2 | sc-200994 sc-200994A | 500 µg 1 mg | $171.00 $286.00 | 7 | |
Apamin selectively blocks small conductance calcium-activated potassium channels (SK channels), potentially affecting KCNRG. | ||||||
4-Aminopyridine | 504-24-5 | sc-202421 sc-202421B sc-202421A | 25 g 1 kg 100 g | $38.00 $1155.00 $122.00 | 3 | |
4-Aminopyridine is a potassium channel blocker, particularly affecting voltage-gated potassium channels, and might influence KCNRG. | ||||||
Glyburide (Glibenclamide) | 10238-21-8 | sc-200982 sc-200982A sc-200982D sc-200982B sc-200982C | 1 g 5 g 25 g 100 g 500 g | $46.00 $61.00 $117.00 $173.00 $530.00 | 36 | |
Glibenclamide inhibits ATP-sensitive potassium channels, potentially impacting KCNRG regulation. | ||||||
Quinine | 130-95-0 | sc-212616 sc-212616A sc-212616B sc-212616C sc-212616D | 1 g 5 g 10 g 25 g 50 g | $79.00 $104.00 $166.00 $354.00 $572.00 | 1 | |
Quinine modulates various ion channels, including potassium channels, potentially influencing KCNRG. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
Nifedipine, a calcium channel blocker, might indirectly affect potassium channel regulation and hence KCNRG. | ||||||