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JNK2 Inhibitors

JNK2 inhibitors constitute a distinctive category within the realm of chemical compounds that are meticulously designed to target and modulate the activity of the JNK2 enzyme, a prominent member of the c-Jun N-terminal kinase (JNK) family. These inhibitors have garnered substantial interest due to their ability to interact selectively with the JNK2 enzyme, which holds a central role in various intricate cellular signaling pathways. JNK2, belonging to the mitogen-activated protein kinase (MAPK) family, functions as a vital mediator of diverse cellular processes, including proliferation, differentiation, apoptosis, and response to external stressors. The design and development of JNK2 inhibitors demand a profound comprehension of the enzyme's molecular structure, catalytic mechanisms, and the intricate network of interactions that regulate its activation and downstream effects. Researchers employ this knowledge to engineer compounds that specifically target JNK2, aiming to modulate its enzymatic activity without affecting other members of the JNK family. These inhibitors often operate through mechanisms such as competitive binding to the enzyme's active site or allosteric modulation, disrupting the transduction of signals along the JNK2-mediated signaling pathways. As a result, these compounds contribute to a more refined understanding of the complex regulatory mechanisms orchestrated by the JNK2 enzyme. In various experimental contexts, JNK2 inhibitors have proven valuable tools for unraveling the functional roles of the JNK2 enzyme within intricate cellular processes. By perturbing the JNK2-mediated signaling cascades, researchers can decipher the nuanced relationships between this enzyme and its downstream targets, shedding light on the intricate orchestration of cellular responses.

Items 1 to 10 of 15 total

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Product Name	CAS #	Catalog #	QUANTITY	Price	Citations	RATING
SP600125	129-56-6	sc-200635 sc-200635A	10 mg 50 mg	$40.00 $150.00	257	(3)
SP600125 (CAS 129-56-6) is a chemical compound known for its role as a selective inhibitor of JNK2, a signaling protein. It modulates JNK2 activity without involving clinical applications, demonstrating its significance in cellular research.
JNK Inhibitor VIII	894804-07-0	sc-202673	5 mg	$272.00	2	(1)
JNK Inhibitor VIII (CAS 894804-07-0) is a chemical compound recognized for its capacity to inhibit JNK2, a signaling protein. It influences JNK2 activity, offering valuable insights in cellular investigations, without venturing into clinical or drug-related domains.
JNK Inhibitor XVI	1410880-22-6	sc-364745	10 mg	$357.00	5	(1)
JNK Inhibitor XVI (CAS 1410880-22-6) is a chemical compound acknowledged for its role in inhibiting JNK2, a signaling protein. It modulates JNK2 activity, contributing to cellular research endeavors.
JNK Inhibitor IX	312917-14-9	sc-202671	5 mg	$226.00	6	(1)
JNK Inhibitor IX (CAS 312917-14-9) is a chemical compound recognized for its ability to inhibit JNK2, a signaling protein. It modulates JNK2 activity, contributing to cellular research, while steering clear of clinical or drug-related contexts.
JNK Inhibitor V	345987-15-7	sc-202672A sc-202672	1 mg 5 mg	$60.00 $169.00	3	(1)
JNK Inhibitor V (CAS 345987-15-7) is a chemical compound known for its role in inhibiting JNK2, a signaling protein. It modulates JNK2 activity, contributing to cellular research pursuits, while avoiding clinical or drug-related discussions.
JNK Inhibitor XIV		sc-364744	10 mg	$379.00		(0)
JNK Inhibitor XIV is a compound known for its capability to inhibit JNK2, a key protein involved in cellular signaling pathways.
L-JNKi1	1445179-97-4 D-isomer	sc-300882	1 mg	$319.00		(0)
L-JNKi1 is a chemical compound known for its role as a JNK2 inhibitor, targeting a specific signaling pathway. It modulates cellular responses by interacting with JNK2, a protein involved in various cellular processes.
JNK Inhibitor XV		sc-364746	25 mg	$209.00		(0)
JNK Inhibitor XV is a compound recognized for its capability to inhibit JNK2, a key protein in cellular signaling. By interacting with JNK2, it influences important cellular responses and pathways.
p38 MAP Kinase Inhibitor IV	1638-41-1	sc-204159	5 mg	$295.00		(0)
p38 MAP Kinase Inhibitor IV (CAS 1638-41-1) is a chemical compound that serves as an inhibitor of JNK2, a signaling protein. It modulates JNK2 activity, contributing to cellular research endeavors.
BI 78D3	883065-90-5	sc-203840 sc-203840A	10 mg 50 mg	$204.00 $810.00	2	(1)
A selective JNK2 inhibitor that exhibits anti-inflammatory properties and has been explored as a potential therapeutic option for inflammatory diseases.

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JNK2 Inhibitors

SP600125

JNK Inhibitor VIII

JNK Inhibitor XVI

JNK Inhibitor IX

JNK Inhibitor V

JNK Inhibitor XIV

L-JNKi1

JNK Inhibitor XV

p38 MAP Kinase Inhibitor IV

BI 78D3