Date published: 2026-4-1

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Jaz Inhibitors

Jaz inhibitors constitute a class of chemical compounds designed to target and interfere with the activity of proteins or molecules associated with the JAZ family. JAZ stands for Jasmonate-ZIM domain proteins, which are essential components in plant signaling pathways. These inhibitors are developed with the aim of modulating the function of JAZ proteins or related molecules, which are primarily involved in regulating various physiological processes in plants, such as responses to stress, defense against herbivores, and growth and development.

The primary mechanism of action for Jaz inhibitors typically involves their interaction with JAZ proteins or associated molecules, leading to the disruption of their normal functions. By inhibiting JAZ proteins, these compounds may potentially influence the signaling pathways that govern plant responses to environmental stimuli. Researchers studying Jaz inhibitors aim to elucidate the specific roles and functions of JAZ proteins and related components in plant biology, contributing to our understanding of their significance in plant growth, development, and adaptation to changing conditions. These inhibitors serve as valuable tools for advancing our knowledge of plant molecular biology and signaling pathways, facilitating research into how plants respond to various environmental cues. In this context, they contribute to expanding our understanding of the complex world of plant physiology and adaptation.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Mitoxantrone

65271-80-9sc-207888
100 mg
$285.00
8
(1)

Mitoxantrone intercalates into DNA and inhibits topoisomerase II, potentially disrupting ZNF346-mediated transcription.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Actinomycin D binds to DNA and inhibits transcriptional elongation, which could reduce the expression of genes regulated by ZNF346.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$58.00
$186.00
$94.00
21
(2)

Camptothecin inhibits topoisomerase I, leading to DNA damage and potentially affecting the activity of DNA-binding proteins like ZNF346.

Quinomycin A

512-64-1sc-202306
1 mg
$166.00
4
(1)

A DNA-binding compound that could impede the binding of ZNF346 to its target DNA sequences.

Chromomycin A3

7059-24-7sc-200907
10 mg
$260.00
(1)

Chromomycin A3 binds to GC-rich regions of DNA, potentially disrupting ZNF346-DNA interactions.

Aminopterin

54-62-6sc-202461
50 mg
$102.00
1
(1)

Aminopterin inhibits dihydrofolate reductase, leading to reduced DNA synthesis, and could consequently affect ZNF346 levels.

Aphidicolin

38966-21-1sc-201535
sc-201535A
sc-201535B
1 mg
5 mg
25 mg
$84.00
$306.00
$1104.00
30
(3)

Aphidicolin selectively inhibits DNA polymerase, which could indirectly decrease ZNF346 expression.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

Triptolide has been shown to inhibit transcriptional activity broadly and may indirectly affect ZNF346 expression.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$135.00
$1085.00
115
(2)

Bortezomib inhibits the proteasome, leading to increased protein degradation, which could theoretically reduce ZNF346 levels.