Date published: 2026-5-24

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IRS CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. IRS gene silencers are available as IRS CRISPR/Cas9 Knockout plasmids and IRS Double Nickase Plasmids. IRS CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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IRS CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IRS-1 CRISPR/Cas9 KO Plasmid (h2)

sc-400096-KO-2hGene KnockoutGFP0
(0)

IRS-1 HDR Plasmid (h2)

sc-400096-HDR-2hHomology Directed RepairPuromycin0
(0)

IRS-1 Double Nickase Plasmid (h)

sc-400096-NIChGene KnockoutPuromycin0
(0)

IRS-1 Double Nickase Plasmid (h2)

sc-400096-NIC-2hGene KnockoutPuromycin0
(0)

IRS-1 CRISPR/Cas9 KO Plasmid (m2)

sc-421150-KO-2mGene KnockoutGFP0
(0)

IRS-2 CRISPR/Cas9 KO Plasmid (h)

sc-400474hGene KnockoutGFP0
(0)

IRS-2 HDR Plasmid (h2)

sc-400474-HDR-2hHomology Directed RepairPuromycin0
(0)

IRS-2 Double Nickase Plasmid (h)

sc-400474-NIChGene KnockoutPuromycin0
(0)

IRS-2 Double Nickase Plasmid (h2)

sc-400474-NIC-2hGene KnockoutPuromycin0
(0)

IRS-2 CRISPR/Cas9 KO Plasmid (m)

sc-436438mGene KnockoutGFP0
(0)

IRS-2 HDR Plasmid (m)

sc-436438-HDRmHomology Directed RepairPuromycin0
(0)

IRS-3 CRISPR/Cas9 KO Plasmid (m)

sc-421151mGene KnockoutGFP0
(0)

IRS-4 CRISPR/Cas9 KO Plasmid (h)

sc-402033hGene KnockoutGFP0
(0)

IRS CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IRS-1 CRISPR Activation Plasmid (h)

sc-400096-ACThGene ActivationPuro, Blast, Hygro0
(0)

IRS-1 CRISPR Activation Plasmid (h2)

sc-400096-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IRS-2 CRISPR Activation Plasmid (h)

sc-400474-ACThGene ActivationPuro, Blast, Hygro0
(0)

IRS-4 CRISPR Activation Plasmid (h)

sc-402033-ACThGene ActivationPuro, Blast, Hygro0
(0)