Date published: 2026-4-10

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IRF-3 Antibodies

Santa Cruz Biotechnology delivers a wide array of IRF-3 monoclonal antibodies for investigating Interferon Regulatory Factor 3. Multiple applications are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Interferon Regulatory Factor 3 functions as a transcription factor with significant involvement in immune response mechanisms, particularly in regulating type I interferon production during viral infections. The activation of IRF-3 triggers antiviral gene expression, establishing its importance in innate immunity. Research focused on IRF-3 continues to reveal new insights about viral defense mechanisms and immune system regulation. Understanding IRF-3 pathways and functions helps advance the development of antiviral treatments and therapeutic approaches. Scientists can utilize IRF-3 monoclonal antibodies to examine protein expression, cellular localization, and interaction patterns in various experimental settings. The reliability and specificity of Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to make meaningful contributions to immunology and virology research.

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IRF-3 Antibodies

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IRF3 Antibody (SL-12)

sc-33641mouse IgG1 κ56-427 (h)WB, IP, IF, IHC(P)m, r, h
86
(20)

IRF3 Antibody (SL-14)

sc-33642mouse IgG1 κFL (h)WB, IP, IF, IHC(P)h
3
(4)

IRF3 Antibody (D-3)

sc-376455mouse IgG1 κ389-427 (h)WB, IP, IF, IHC(P), ELISAm, r, h
17
(8)

IRF-3 CRISPR Knockout, HDR and Double Nickase Plasmids

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IRF3 CRISPR/Cas9 KO Plasmid (h)

sc-417171hGene KnockoutGFP
1
(0)

IRF3 HDR Plasmid (h)

sc-417171-HDRhHomology Directed RepairPuromycin
1
(0)

IRF3 Double Nickase Plasmid (h)

sc-417171-NIChGene KnockoutPuromycin
1
(0)

IRF3 Double Nickase Plasmid (h2)

sc-417171-NIC-2hGene KnockoutPuromycin
1
(0)

IRF3 Double Nickase Plasmid (m)

sc-424792-NICmGene KnockoutPuromycin0
(0)

IRF-3 CRISPR Activation Products

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IRF3 CRISPR Activation Plasmid (h)

sc-417171-ACThGene ActivationPuro, Blast, Hygro
1
(0)

IRF-3 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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IRF3 siRNA (h)

sc-35710hGene SilencingN/A
13
(0)

IRF3 shRNA Plasmid (h)

sc-35710-SHhGene SilencingPuromycin
13
(0)

IRF3 shRNA (h) Lentiviral Particles

sc-35710-VhGene SilencingPuromycin
13
(0)

IRF3 siRNA (m)

sc-35711mGene SilencingN/A
2
(0)

IRF3 shRNA Plasmid (m)

sc-35711-SHmGene SilencingPuromycin
2
(0)

IRF3 shRNA (m) Lentiviral Particles

sc-35711-VmGene SilencingPuromycin
2
(0)