Date published: 2026-3-14

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Ionophores

Santa Cruz Biotechnology now offers a broad range of ionophores for use in various applications. Ionophores are a class of chemical compounds that facilitate the transport of ions across cell membranes by forming complexes with specific ions, which can be essential in numerous biochemical and biophysical studies. These compounds are integral to scientific research due to their ability to manipulate ionic concentrations within cells and organelles, making them crucial tools in the study of ion gradients, membrane potentials, and signal transduction pathways. In the field of biochemistry, ionophores are used to dissect the roles of different ions in cellular processes, providing insights into mechanisms such as ATP production, osmoregulation, and metabolic regulation. Their ability to selectively bind and transport ions makes them valuable in analytical chemistry for the detection and quantification of ions in complex mixtures. Environmental scientists utilize ionophores to study ion exchange and transport in natural systems, contributing to our understanding of soil and water chemistry. In materials science, ionophores are employed in the design of ion-selective electrodes and sensors, enhancing the sensitivity and specificity of these devices for various applications. Furthermore, their role in facilitating ion transport is explored in the development of novel materials for energy storage and conversion, such as in the fabrication of advanced batteries and fuel cells. The versatility and specificity of ionophores make them indispensable in a wide array of research disciplines, driving innovation and expanding our understanding of ionic processes. View detailed information on our available ionophores by clicking on the product name.

Items 91 to 100 of 263 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Sisomicin sulfate salt

53179-09-2sc-236885
sc-236885A
250 mg
1 g
$92.00
$309.00
(0)

Sisomicin sulfate salt acts as an ionophore by facilitating the transport of cations across lipid membranes through specific binding interactions. Its structure allows for the formation of transient complexes with ions, enhancing their solubility in the hydrophobic environment of the membrane. This compound exhibits distinct reaction kinetics, characterized by a swift exchange of ions, which can lead to alterations in membrane potential and ionic gradients, impacting cellular processes.

Tiamulin

55297-95-5sc-237107
100 mg
$372.00
1
(0)

Tiamulin, a member of the pleuromutilin class, acts as an ionophore by forming complexes with cations, particularly affecting calcium and magnesium ions. Its unique structure allows for specific interactions with lipid membranes, enhancing permeability and ion transport. The compound exhibits distinct reaction kinetics, characterized by a gradual release of bound ions, which can modulate cellular ion concentrations. Its amphipathic nature aids in membrane integration, influencing ion dynamics and cellular processes.

Trinactin

7561-71-9sc-202370
1 mg
$420.00
(0)

Trinactin functions as an ionophore by facilitating the transport of cations across biological membranes through its unique structural conformation. Its ability to form transient complexes with metal ions enhances their solubility and mobility, allowing for rapid ion exchange. The compound's interaction with lipid bilayers alters membrane permeability, leading to significant changes in ionic flux and cellular signaling pathways. This dynamic behavior highlights its influence on ion distribution and cellular electrochemical balance.

Coumarin 343

55804-65-4sc-252639
100 mg
$32.00
(1)

Coumarin 343 functions as an ionophore by facilitating the transport of cations across biological membranes. Its unique molecular structure enables it to selectively bind to metal ions, promoting their translocation through lipid bilayers. This compound exhibits rapid kinetics in ion exchange, allowing for swift modulation of intracellular ion levels. Additionally, its photophysical properties enhance its interaction with membranes, influencing ion flux and cellular signaling pathways.

Spiramycin

8025-81-8sc-251064
sc-251064A
sc-251064B
1 g
5 g
10 g
$81.00
$176.00
$317.00
1
(0)

Spiramycin acts as an ionophore by selectively binding to cations, promoting their translocation across lipid membranes. Its unique cyclic structure allows for the formation of stable complexes with divalent and monovalent ions, enhancing their diffusion rates. This interaction modifies membrane fluidity and alters ion gradients, which can significantly impact cellular homeostasis and metabolic processes. The compound's affinity for specific ions underscores its role in modulating ionic environments within cells.

Gramicidin A

11029-61-1sc-203061
sc-203061A
1 mg
5 mg
$82.00
$151.00
7
(1)

Gramicidin A acts as an ionophore by forming a channel in lipid membranes, allowing selective passage of monovalent cations, particularly sodium and potassium ions. Its unique helical structure stabilizes ion binding through specific interactions, promoting rapid ion translocation. The dynamic nature of these channels enables a swift response to concentration gradients, significantly affecting membrane potential and ionic homeostasis. This behavior underscores its role in modulating electrochemical environments.

Enniatin complex

11113-62-5sc-202152
10 mg
$459.00
(0)

Enniatin complex functions as an ionophore by forming a unique cyclic structure that facilitates the transport of cations across lipid membranes. Its ability to selectively bind to divalent and monovalent ions is attributed to its hydrophobic and polar regions, which create a favorable environment for ion solvation. The complex exhibits rapid kinetics in ion exchange, significantly influencing cellular ionic balance and membrane potential, thereby impacting electrochemical gradients.

PGB1 (Prostaglandin B1)

13345-51-2sc-201217
sc-201217A
1 mg
10 mg
$37.00
$232.00
(0)

PGB1 operates as an ionophore through its distinctive ability to interact with lipid bilayers, promoting the translocation of ions. Its molecular structure allows for specific binding to cations, enhancing their solubility in the membrane environment. The compound exhibits notable reaction kinetics, facilitating swift ion transport and influencing cellular homeostasis. Additionally, PGB1's unique conformational flexibility enables it to modulate ion selectivity, impacting membrane dynamics and ionic equilibrium.

N-Benzylidenebenzenesulfonamide

13909-34-7sc-250446
5 g
$77.00
(0)

N-Benzylidenebenzenesulfonamide functions as an ionophore by engaging in selective ion binding through its sulfonamide group, which enhances its affinity for cations. This compound exhibits unique conformational flexibility, allowing it to adapt its structure for optimal interaction with target ions. Its hydrophobic benzylidene moiety promotes partitioning into lipid environments, facilitating ion transport across membranes and modulating electrochemical gradients, thereby influencing cellular ionic dynamics.

Monensin A

17090-79-8sc-362032
sc-362032A
5 mg
25 mg
$155.00
$525.00
(1)

Monensin A functions as an ionophore by facilitating the transport of monovalent cations across biological membranes. Its unique structure allows it to form cyclic complexes with sodium and potassium ions, enhancing ion mobility. The presence of a carboxylic acid group contributes to its solubility in lipophilic environments, while its hydrophobic regions promote interaction with lipid bilayers. This selective ion transport alters membrane potential and influences cellular ionic homeostasis.