Molecular structure of Spiramycin, CAS Number: 8025-81-8
Spiramycin (CAS 8025-81-8)
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Alternate Names:
Formacidine
CAS Number:
8025-81-8
Molecular Weight:
843.06
Molecular Formula:
C43H74N2O14
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Spiramycin is a macrolide antibiotic produced by Streptomyces ambofaciens. It is composed of a large lactone ring to which one or more deoxy sugars are attached. Spiramycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, thus preventing the translocation of peptidyl-tRNA from the A-site to the P-site. This ultimately leads to the inhibition of bacterial growth.
Spiramycin (CAS 8025-81-8) References
- Spiramycin resistance in human periodontitis microbiota. | Rams, TE., et al. 2011. Anaerobe. 17: 201-5. PMID: 21524712
- Is sulfadiazine alone equivalent (benefit and harm) to spiramycin to treat acute toxoplasmosis in the first trimester of pregnancy? | Bernardo, WM., et al. 2015. Rev Assoc Med Bras (1992). 61: 495-6. PMID: 26841157
- Municipal wastewater spiramycin removal by conventional treatments and heterogeneous photocatalysis. | Lofrano, G., et al. 2018. Sci Total Environ. 624: 461-469. PMID: 29268218
- Spiramycin-related cutaneous eruption confirmed by patch testing. | Poveda-Montoyo, I., et al. 2018. Contact Dermatitis. 78: 233-234. PMID: 29430709
- Rapid thermal-acid hydrolysis of spiramycin by silicotungstic acid under microwave irradiation. | Chen, Z., et al. 2019. Environ Pollut. 249: 36-44. PMID: 30878860
- Spiramycin adsorption behavior on activated bentonite, activated carbon and natural phosphate in aqueous solution. | El Maataoui, Y., et al. 2019. Environ Sci Pollut Res Int. 26: 15953-15972. PMID: 30963430
- The regulatory genes involved in spiramycin and bitespiramycin biosynthesis. | Dai, J., et al. 2020. Microbiol Res. 240: 126532. PMID: 32622100
- A fresh look at the role of spiramycin in preventing a neglected disease: meta-analyses of observational studies. | Montoya, JG., et al. 2021. Eur J Med Res. 26: 143. PMID: 34895348
- Preparation of spiramycin fermentation residue derived biochar for effective adsorption of spiramycin from wastewater. | Gao, T., et al. 2022. Chemosphere. 296: 133902. PMID: 35143862
- Anti-Inflammatory Effects of Spiramycin in LPS-Activated RAW 264.7 Macrophages. | Kang, JK., et al. 2022. Molecules. 27: PMID: 35630676
- A high-performance SERS imprinted membrane based on Ag/CNTs for selective detection of spiramycin. | Li, H., et al. 2022. Spectrochim Acta A Mol Biomol Spectrosc. 281: 121587. PMID: 35797948
- Evaluation of spiramycin for topical applications: a cell culture study. | Yagiz Aghayarov, O., et al. 2023. Eur Rev Med Pharmacol Sci. 27: 44-50. PMID: 36971220
- Kinetic study of irreversible inhibition of an enzyme consumed in the reaction it catalyses. Application to the inhibition of the puromycin reaction by spiramycin and hydroxylamine. | Dinos, GP. and Coutsogeorgopoulos, C. 1997. J Enzyme Inhib. 12: 79-99. PMID: 9247852
Inhibitor of:
Cryptosporidium parvum.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Spiramycin, 1 g | sc-251064 | 1 g | $79.00 | |||
Spiramycin, 5 g | sc-251064A | 5 g | $173.00 | |||
Spiramycin, 10 g | sc-251064B | 10 g | $311.00 |