Date published: 2026-5-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

PGB1 (Prostaglandin B1) (CAS 13345-51-2)

0.0(0)
Write a reviewAsk a question

Application:
PGB1 (Prostaglandin B1) is a metabolite of PGA1 shown to modify the pressor responses to sympathetic nerve stimulation
CAS Number:
13345-51-2
Purity:
>98%
Molecular Weight:
336.5
Molecular Formula:
C20H32O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

PGB1 (Prostaglandin B1) is a nonenzymatic dehydration product of PGE1(sc-201223) and a metabolite of PGA1(sc-201213) that may act to modify the pressor responses to sympathetic nerve stimulation. Furthermore, when PGB1 (Prostaglandin B1) is oligomerized it may act to inhibit phospholipase A2, and act as an ionophore for calcium. In cellular and molecular biology, PGB1 (Prostaglandin B1) can be utilized to study signal transduction pathways involved in cell growth, death, and differentiation. Its impact on various cell types helps elucidate the roles of prostaglandins in cellular functions. The synthesis and structural modification of PGB1 (Prostaglandin B1) contribute to the field of synthetic organic chemistry, where techniques to create and modify prostaglandins can be applied to other complex molecules, advancing the development of synthetic methodologies.


PGB1 (Prostaglandin B1) (CAS 13345-51-2) References

  1. A novel synthesis of racemic and enantiomeric forms of prostaglandin B1 methyl ester.  |  Mikołajczyk, M., et al. 2000. J Org Chem. 65: 5127-30. PMID: 10993336
  2. Calcium ionophore activity of a prostaglandin B1 derivative (PGBx).  |  Ohnishi, ST. and Devlin, TM. 1979. Biochem Biophys Res Commun. 89: 240-5. PMID: 113006
  3. Oligomers of prostaglandin B1 inhibit arachidonic acid mobilization in human neutrophils and endothelial cells.  |  Rosenthal, MD. and Franson, RC. 1989. Biochim Biophys Acta. 1006: 278-86. PMID: 2557075
  4. Oligomers of prostaglandin B1 inhibit in vitro phospholipase A2 activity.  |  Franson, RC. and Rosenthal, MD. 1989. Biochim Biophys Acta. 1006: 272-7. PMID: 2597672
  5. Separation and molecular weight determination of prostaglandin B1 oligomers by size-exclusion chromatography.  |  Martin, I. and Lille, U. 1989. J Chromatogr. 466: 339-45. PMID: 2745616
  6. Calcium ionophoretic activity of chemically synthesized oligomeric derivatives of prostaglandin B1.  |  Uribe, S., et al. 1987. Biochim Biophys Acta. 924: 87-98. PMID: 3828398
  7. Metabolism of prostaglandins in rat liver mitochondria.  |  Hamberg, M. 1968. Eur J Biochem. 6: 135-46. PMID: 5725806
  8. Inhibition of oxidative phosphorylation by an oligomer of prostaglandin B1, PGBx.  |  Kreutter, DK. and Devlin, TM. 1983. Arch Biochem Biophys. 221: 216-26. PMID: 6187287
  9. Quantitative determination of prostaglandins A1 and B1 in alprostadil (PGE1) by high-performance liquid chromatography.  |  Zoutendam, PH., et al. 1984. J Chromatogr. 283: 281-7. PMID: 6538575
  10. Inhibition of human malignant melanoma colony-forming cells in vitro by prostaglandin A1.  |  Bregman, MD. and Meyskens, FL. 1983. Cancer Res. 43: 1642-5. PMID: 6572555
  11. Prostaglandin B1 can modify the pressor responses to sympathetic nerve stimulation.  |  Himori, N. and Burkman, AM. 1983. Res Commun Chem Pathol Pharmacol. 41: 397-405. PMID: 6635328
  12. Microdetermination of the prostaglandin B1 in human plasma by gas chromatography/selected ion monitoring using [18O]prostaglandin B1 as an internal standard.  |  Hishinuma, T., et al. 1995. Prostaglandins. 49: 239-46. PMID: 7667505
  13. Enhancement of neural and thermal vasoconstriction by prostaglandin B1.  |  Engelbrecht, JA., et al. 1975. Proc Soc Exp Biol Med. 148: 729-33. PMID: 805432

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

PGB1 (Prostaglandin B1), 1 mg

sc-201217
1 mg
$37.00

PGB1 (Prostaglandin B1), 10 mg

sc-201217A
10 mg
$232.00