Intelectin-2 Inhibitors
Intelectin-2 inhibitors belong to a specific class of chemical compounds that have attracted interest in the field of immunology and host-pathogen interactions. Intelectin-2, also known as Omentin-2, is a protein expressed in various tissues, including adipose tissue and the gastrointestinal tract. It belongs to the intelectin protein family, which plays a role in innate immunity by recognizing and binding to carbohydrate structures on the surface of pathogens. Intelectin-2, in particular, is involved in the recognition of microbial glycans and has been implicated in host defense mechanisms against bacterial and fungal infections. Intelectin-2 inhibitors are chemical compounds designed to interact with Intelectin-2, potentially modulating its functions and affecting its ability to recognize and bind to pathogens.
The mechanism of action of Intelectin-2 inhibitors typically involves their binding to specific sites or domains within the Intelectin-2 protein. This interaction can lead to changes in Intelectin-2's ability to recognize microbial glycans, potentially impacting its role in host defense and immune responses to pathogens. Consequently, Intelectin-2 inhibitors may have implications for understanding the molecular mechanisms underlying innate immunity and the host's ability to recognize and respond to microbial infections. They provide valuable tools for investigating the roles of Intelectin-2 in the immune system, shedding light on the complex interplay between host and pathogen at the molecular level.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Interacts with DNA and inhibits RNA polymerase, which could reduce Intelectin-2 mRNA synthesis. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Inhibits bacterial RNA polymerase and might affect host transcription factors, potentially reducing Intelectin-2 expression. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Known to affect lysosomal function and may influence gene expression patterns, including Intelectin-2. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor which could alter chromatin structure and decrease Intelectin-2 gene expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
As an HDAC inhibitor, it could modify histones leading to changes in gene expression, possibly affecting Intelectin-2. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
A DNA methyltransferase inhibitor that can change the methylation status of genes, potentially reducing Intelectin-2 expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
Inhibits eukaryotic RNA polymerase II and III, which could downregulate Intelectin-2 mRNA production. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
A proteasome inhibitor that affects NF-kB pathway and could influence Intelectin-2 expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another HDAC inhibitor that may change the epigenetic landscape and alter Intelectin-2 expression. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Inhibits N-linked glycosylation which could affect the maturation and stability of mRNA, including that of Intelectin-2. | ||||||