Integrin α9 Activators
The Integrin α9 Activators represent a distinctive group of chemicals that intricately modulate cellular processes by directly or indirectly influencing the activity of Integrin α9. Among these, E7820, a chemical compound influencing the VEGFR2/FAK pathway, showcases the interconnectedness of signaling cascades, indirectly enhancing Integrin α9 activity. SNS-032, a selective CDK inhibitor, indirectly activates Integrin α9 through the p53/MDM2 pathway, revealing the intricate cross-talk between cell cycle regulation and integrin activity. LY294002, a PI3K inhibitor, disrupts downstream signaling events, resulting in enhanced Integrin α9 activity and modulation of associated cellular processes.
The Integrin α9 Activators also include compounds like Y-27632, a selective ROCK inhibitor, and SU6656, a Src family kinase inhibitor, both influencing integrin activity through specific pathway modulation. PF-573228, a potent FAK inhibitor, and SB 431542, an ALK5 inhibitor, further illustrate the diversity of chemical compounds capable of indirectly activating Integrin α9 by targeting specific signaling pathways. In summary, the Integrin α9 Activators exemplify a diverse array of chemicals that, through precise modulation of signaling pathways, intricately influence the activity of Integrin α9. These compounds serve as valuable tools for researchers exploring the complex regulatory networks involving Integrin α9 and contribute to a deeper understanding of the molecular mechanisms governing cellular processes associated with Integrin α9 functions.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
E7820 | 289483-69-8 | sc-507333 | 10 mg | $102.00 | ||
E7820 is a chemical compound that indirectly activates Integrin α9 by influencing the VEGFR2/FAK pathway. By inhibiting VEGFR2 and FAK, E7820 disrupts downstream signaling events, resulting in enhanced Integrin α9 activity and modulation of cellular processes associated with Integrin α9 functions. | ||||||
SNS-032 | 345627-80-7 | sc-364621 sc-364621A | 5 mg 10 mg | $169.00 $262.00 | ||
SNS-032 is a selective CDK inhibitor that indirectly activates Integrin α9 by influencing the p53/MDM2 pathway. Through inhibition of CDKs, SNS-032 stabilizes p53 and disrupts MDM2-mediated inhibition of Integrin α9, leading to increased integrin activity and modulation of cellular processes associated with Integrin α9 functions. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor that indirectly activates Integrin α9 by inhibiting the PI3K/Akt pathway. By blocking PI3K, LY294002 disrupts downstream signaling events, resulting in enhanced Integrin α9 activity and modulation of cellular processes associated with Integrin α9 functions. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 is a selective inhibitor of Rho-associated protein kinase (ROCK) that indirectly activates Integrin α9 by modulating the Rho/ROCK pathway. By inhibiting ROCK, Y-27632 disrupts the negative regulation of Integrin α9 activation, leading to increased integrin activity and modulation of cellular processes associated with Integrin α9 functions. | ||||||
SU6656 | 330161-87-0 | sc-203286 sc-203286A | 1 mg 5 mg | $57.00 $133.00 | 27 | |
SU6656 is a selective Src family kinase inhibitor that indirectly activates Integrin α9 by influencing the Src/FAK pathway. Through inhibition of Src family kinases, SU6656 disrupts downstream signaling events, resulting in enhanced Integrin α9 activity and modulation of cellular processes associated with Integrin α9 functions. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
SB 431542 is a selective inhibitor of the TGF-β type I receptor ALK5 that indirectly activates Integrin α9 by modulating the TGF-β pathway. By inhibiting ALK5, SB 431542 disrupts TGF-β signaling, leading to increased Integrin α9 activity and modulation of cellular processes associated with Integrin α9 functions. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
PP2 is a selective inhibitor of Src family kinases that indirectly activates Integrin α9 by influencing the Src/FAK pathway. Through inhibition of Src family kinases, PP2 disrupts downstream signaling events, resulting in enhanced Integrin α9 activity and modulation of cellular processes associated with Integrin α9 functions. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB 203580 is a selective inhibitor of p38 MAPK that indirectly activates Integrin α9 by modulating the p38 MAPK pathway. By inhibiting p38 MAPK, SB 203580 disrupts downstream signaling events, resulting in enhanced Integrin α9 activity and modulation of cellular processes associated with Integrin α9 functions. | ||||||