Integrin α9/β1/ITGA9/ITGB1 Antibody (2Q954): sc-71428

Integrin α9/β1 Antibody (2Q954) is a mouse monoclonal IgG1 kappa light chain antibody that detects the Integrin alpha 9/beta 1 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Anti-Integrin α9/β1 antibody (2Q954) is available in both non-conjugated and various conjugated forms, including phycoerythrin (PE) and fluorescein isothiocyanate (FITC), to suit diverse experimental needs. Integrin alpha 9/beta 1 plays a crucial role in cell adhesion and signaling, functioning as a receptor that mediates interactions between cells and the extracellular matrix. Integrin α9/β1 (2Q954) monoclonal antibody is particularly important in the immune system and during tissue repair processes, as Integrin alpha 9/beta 1 facilitates the migration of immune cells to sites of inflammation and injury. Integrin alpha 9/beta 1 is primarily located on the cell surface, where Integrin alpha 9/beta 1 interacts with ligands such as fibronectin and collagen, which are essential for maintaining tissue integrity and facilitating cellular communication. The binding of Integrin alpha 9/beta 1 to these ligands not only supports cell adhesion but also triggers intracellular signaling pathways that influence cell behavior, including proliferation and survival. Using Integrin α9/β1 (2Q954) antibody in research can provide valuable insights into the mechanisms of cell adhesion and migration, which are vital for understanding various physiological and pathological processes.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Integrin α9/β1/ITGA9/ITGB1 Antibody (2Q954) References:

1. Structural requirement of carboxyl-terminal globular domains of laminin alpha 3 chain for promotion of rapid cell adhesion and migration by laminin-5.  |  Hirosaki, T., et al. 2000. J Biol Chem. 275: 22495-502. PMID: 10801807
2. Integrins: versatility, modulation, and signaling in cell adhesion.  |  Hynes, RO. 1992. Cell. 69: 11-25. PMID: 1555235
3. Identification of human galactoprotein b3, an oncogenic transformation-induced membrane glycoprotein, as VLA-3 alpha subunit: the primary structure of human integrin alpha 3.  |  Tsuji, T., et al. 1991. J Biochem. 109: 659-65. PMID: 1714443
4. Integrin alpha9 beta1 is a receptor for nerve growth factor and other neurotrophins.  |  Staniszewska, I., et al. 2008. J Cell Sci. 121: 504-13. PMID: 18230652
5. Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage.  |  Lydolph, MC., et al. 2009. Exp Cell Res. 315: 3312-24. PMID: 19796635
6. The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour.  |  Høye, AM., et al. 2016. Sci Rep. 6: 28529. PMID: 27339664
7. Integrin heterodimer α9 β1 is localized on the surface of porcine spermatogonial stem cells in the undifferentiated state.  |  Park, MH., et al. 2019. Reprod Domest Anim. 54: 1497-1500. PMID: 31442342
8. Integrins and signal transduction pathways: the road taken.  |  Clark, EA. and Brugge, JS. 1995. Science. 268: 233-9. PMID: 7716514
9. Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.  |  Miyamoto, S., et al. 1995. Science. 267: 883-5. PMID: 7846531
10. Epithelial integrins.  |  Sheppard, D. 1996. Bioessays. 18: 655-60. PMID: 8760339
11. Cooperation between soluble factors and integrin-mediated cell anchorage in the control of cell growth and differentiation.  |  Juliano, R. 1996. Bioessays. 18: 911-7. PMID: 8939069
12. The A and B variants of the alpha 3 integrin subunit: tissue distribution and functional characterization.  |  de Melker, AA., et al. 1997. Lab Invest. 76: 547-63. PMID: 9111516

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Integrin α9/β1/ITGA9/ITGB1 Antibody (2Q954) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-Integrin α9/β1/ITGA9/ITGB1 Antibody (2Q954) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Integrin α9/β1/ITGA9/ITGB1 Antibody (2Q954) Specifications

Alternate Product Name: CD29

Product Clone Name: 2Q954

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: Integrin α9/β1

Epitope Species: human

Product Reactivity/Detection: Integrin α9 and Integrin β1

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), FCM

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Integrin α9/β1/ITGA9/ITGB1 Antibody (2Q954): FITC: Fluoroscein, PE: Phycoerythrin

The preferred Integrin β1/ITGB1 antibody is Integrin β1/ITGB1 Antibody (K-20): sc-18887.