INOC1 Activators refers to a specific chemical class characterized by compounds that exhibit the ability to modulate the INOC1 pathway. The INOC1 pathway, standing for Inositol Auxotrophy, Carbon Limitation, and Oxidative Stress Response 1, is a signaling cascade found in various biological systems. Activators of this pathway are substances that trigger or enhance the activity of INOC1, leading to downstream cellular responses. The chemical entities falling within this class typically interact with specific receptors or enzymes associated with the INOC1 pathway, initiating a cascade of molecular events.
Structurally diverse, INOC1 Activators may encompass small molecules, peptides, or other organic compounds that possess the capacity to bind selectively to key components of the INOC1 pathway. Understanding the precise mechanisms by which these compounds engage with the pathway is essential for unraveling their potential biological effects. Researchers investigate the structural motifs and binding sites involved in the interaction between INOC1 Activators and the components of the INOC1 pathway to gain insights into the regulatory mechanisms of cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a potent activator of Protein Kinase C (PKC). PKC signaling is involved in multiple cell processes, including the regulation of proteins. The activation of PKC can lead to phosphorylation and activation of INOC1. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is an activator of adenylate cyclase, which increases levels of cyclic AMP (cAMP) in cells. cAMP acts as a secondary messenger in cells and can activate protein kinase A (PKA). PKA can phosphorylate and enhance the INOC1 protein. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine is a hormone and neurotransmitter that activates the beta-adrenergic receptor. This receptor can activate adenylate cyclase, leading to an increase in cAMP and resulting in the activation of PKA, which can enhance the INOC1 protein. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram is a selective inhibitor of phosphodiesterase 4 (PDE4), which breaks down cAMP. By inhibiting PDE4, Rolipram increases cAMP levels, which can lead to the activation of PKA and subsequently enhance INOC1. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin activates the insulin receptor, which leads to activation of the PI3K/Akt pathway. Activation of Akt can enhance the INOC1 protein. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor. By inhibiting PI3K, it can increase the activation of other pathways, such as the MAPK pathway, which can enhance the INOC1 protein. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is a natural phenol that can activate SIRT1. SIRT1 is involved in cellular regulation (including the aging process) and can interact with various signaling pathways that enhance the INOC1 protein. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is a natural phenol that can inhibit NF-kB, a protein complex that controls DNA transcription. By inhibiting NF-kB, curcumin can enhance the activation of other pathways, such as the MAPK pathway, which can enhance the INOC1 protein. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein is a phytoestrogen and tyrosine kinase inhibitor. By inhibiting tyrosine kinases, genistein can enhance the activation of other pathways, such as the PI3K/Akt pathway, which can enhance the INOC1 protein. | ||||||