Inhibitors Inhibitors
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lonidamine | 50264-69-2 | sc-203115 sc-203115A | 5 mg 25 mg | $103.00 $357.00 | 7 | |
Lonidamine directly inhibits SLC16A, blocking the transport of lactate and disrupting cellular metabolism. | ||||||
Bumetanide (Ro 10-6338) | 28395-03-1 | sc-200727 sc-200727A | 1 g 5 g | $107.00 $224.00 | 9 | |
Bumetanide, though primarily a diuretic, has been shown to inhibit SLC16A indirectly, likely by affecting associated cellular processes. | ||||||
Cabozantinib L-Malate Salt | 1140909-48-3 | sc-504572 | 10 mg | $270.00 | ||
AR-C155858 is a potent and selective inhibitor of MCT2. It inhibits lactate transport by blocking the MCT2 transporter, preventing lactate uptake by cells. | ||||||
UK 5099 | 56396-35-1 | sc-361394 sc-361394A | 10 mg 50 mg | $154.00 $633.00 | 5 | |
UK5099 is a well-known inhibitor of SLC16A and MCT2. It disrupts the mitochondrial pyruvate carrier and indirectly inhibits lactate transport. | ||||||
Gabaculine | 59556-17-1 | sc-200473 sc-200473A sc-200473B | 10 mg 50 mg 250 mg | $347.00 $867.00 $3009.00 | 5 | |
Inhibits GABA transaminases, structurally similar to the substrate of SLC16A, so may bind to and inhibit SLC16A. | ||||||
Trimethoprim | 738-70-5 | sc-203302 sc-203302A sc-203302B sc-203302C sc-203302D | 5 g 25 g 250 g 1 kg 5 kg | $66.00 $158.00 $204.00 $707.00 $3334.00 | 4 | |
Inhibits serine/threonine kinase, potentially altering phosphorylation states impacting SLC16A activity. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Inhibits dihydrofolate reductase, could lead to accumulation of metabolites that indirectly inhibit SLC16A. | ||||||
Methylene blue | 61-73-4 | sc-215381B sc-215381 sc-215381A | 25 g 100 g 500 g | $42.00 $102.00 $322.00 | 3 | |
A redox cycling agent, can modulate cellular redox states that might affect SLC16A activity. | ||||||
Phenethyl-hydrazine | 51-71-8 | sc-331686 | 500 mg | $388.00 | ||
A non-selective inhibitor of monoamine oxidase, could alter metabolic pathways related to SLC16A. | ||||||
Hydroxylamine solution | 7803-49-8 | sc-250136 | 100 ml | $71.00 | ||
General aminotransferase inhibitor, could inhibit SLC16A through covalent modification of the active site. | ||||||