Inhibin β-A Inhibitors
Inhibin β-A inhibitors, as listed above, primarily act indirectly due to the nature of Inhibin β-A's role in protein-protein interactions and its involvement in complex signaling pathways. Inhibin β-A, as part of the inhibin and activin molecules, regulates a multitude of physiological processes, notably in the reproductive system. The inhibitors target various signaling pathways such as TGF-β, activin, and BMP pathways, which are intricately connected with the function of Inhibin β-A.
Compounds like SB-431542, LDN-193189, and Dorsomorphin are key examples of indirect inhibitors. They modulate the activity of receptors and kinases involved in signaling pathways that Inhibin β-A influences. For instance, ALK inhibitors such as SB-431542 and A-83-01 can alter activin signaling, thereby impacting the physiological roles where Inhibin β-A is a critical regulator. Similarly, inhibitors of BMP signaling pathways, like LDN-193189 and DMH1, indirectly affect the balance between activin and BMP signaling, which is crucial for the roles Inhibin β-A plays in the body.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
SB-431542 inhibits the activin receptor-like kinase (ALK) receptors, which can indirectly affect Inhibin β-A's role in activin signaling. | ||||||
4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline | 1062368-24-4 | sc-476297 | 5 mg | $240.00 | ||
LDN-193189, a BMP signaling inhibitor, may influence Inhibin β-A activity by modulating the balance between activin and BMP signaling. | ||||||
Dorsomorphin dihydrochloride | 1219168-18-9 | sc-361173 sc-361173A | 10 mg 50 mg | $186.00 $751.00 | 28 | |
Dorsomorphin inhibits BMP type I receptors, potentially affecting Inhibin β-A-related pathways and their biological effects. | ||||||
A 83-01 | 909910-43-6 | sc-203791 sc-203791A | 10 mg 50 mg | $202.00 $811.00 | 16 | |
A-83-01 inhibits ALK receptors, impacting signaling pathways that involve Inhibin β-A and its associated proteins. | ||||||
ALK5 Inhibitor II | 446859-33-2 | sc-221234 sc-221234A sc-221234B sc-221234C sc-221234D sc-221234E sc-221234F | 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 g | $77.00 $153.00 $219.00 $663.00 $1248.00 $4382.00 $7850.00 | 8 | |
RepSox, an ALK5 inhibitor, can alter TGF-β signaling pathways, indirectly influencing Inhibin β-A's function. | ||||||
LY2157299 | 700874-72-2 | sc-391123 sc-391123A | 5 mg 10 mg | $213.00 $359.00 | 3 | |
LY2157299, another inhibitor of TGF-β receptor kinase, could impact the biological roles of Inhibin β-A through TGF-β pathway modulation. | ||||||
GW788388 | 452342-67-5 | sc-363544 sc-363544A | 5 mg 25 mg | $95.00 $384.00 | ||
GW788388, an inhibitor of TGF-β receptor I kinase, may indirectly influence Inhibin β-A activity through TGF-β signaling alterations. | ||||||
TGF-β RI Kinase Inhibitor V | 627536-09-8 | sc-203294 | 2 mg | $88.00 | 3 | |
SD-208, targeting TGF-β receptor I kinase, could affect Inhibin β-A's function by modulating the TGF-β signaling pathway. | ||||||
LY 364947 | 396129-53-6 | sc-203122 sc-203122A | 5 mg 10 mg | $107.00 $156.00 | 4 | |
LY364947 inhibits TGF-β receptor I kinase, potentially impacting Inhibin β-A-related signaling pathways. | ||||||
DMH-1 | 1206711-16-1 | sc-361171 sc-361171B sc-361171A sc-361171C | 10 mg 25 mg 50 mg 100 mg | $213.00 $318.00 $632.00 $1047.00 | 2 | |
DMH1, a selective BMP receptor inhibitor, can influence the activity or expression of Inhibin β-A by affecting BMP signaling. | ||||||