Date published: 2025-10-21

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IL-6 Antibodies

Santa Cruz Biotechnology features a diverse variety of IL-6 monoclonal antibodies for investigating interleukin-6 in various biological processes. IL-6 monoclonal antibodies are compatible with multiple research applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).Interleukin-6 is a cytokine that plays a crucial role in immune response, inflammation, and hematopoiesis. IL-6 is involved in the regulation of metabolic, regenerative, and neural processes, making it a key player in both health and disease. Dysregulation of IL-6 has been implicated in various conditions, including autoimmune diseases, chronic inflammatory disorders, and certain cancers. IL-6 signaling pathways influence cellular communication and immune system responses. Understanding IL-6 function and regulation provides critical insights into disease mechanisms and potential treatments. Monitoring IL-6 activity helps researchers track inflammatory responses and immune system activation. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of IL-6 biology and its role in human health and disease.

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IL-6 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IL-6 Antibody (E-4)

sc-28343mouse IgG2a κ30-212 (h)WB, IP, IF, IHC(P), ELISAh
99
(39)

IL-6 Antibody (1)

sc-130326mouse IgG2b κ(h)WB, IP, IF, IHC(P)h
87
(11)

IL-6 Antibody (10E5)

sc-57315mouse IgG2b κFL (r)WB, IP, FCM, ELISAm, r
162
(27)

IL-6 Antibody (C12-1-hIL-6)

sc-32296mouse IgG2a κ(h)WB, IPm, r, h
52
(10)

IL-6 Antibody (6D9A1)

sc-65989mouse IgM κ(h)WB, IPh
4
(1)

IL-6 Antibody (AH65)

sc-53865mouse IgG1 κ(h)WB, IP, ELISAh
1
(1)

IL-6 Antibody (B-F6)

sc-65327mouse IgG1(h)WB, IPh
1
(1)

IL-6 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-6 CRISPR/Cas9 KO Plasmid (h)

sc-400390hGene KnockoutGFP
2
(0)

IL-6 HDR Plasmid (h)

sc-400390-HDRhHomology Directed RepairPuromycin
2
(0)

IL-6 Double Nickase Plasmid (h)

sc-400390-NIChGene KnockoutPuromycin
2
(0)

IL-6 Double Nickase Plasmid (h2)

sc-400390-NIC-2hGene KnockoutPuromycin
2
(0)

IL-6 CRISPR/Cas9 KO Plasmid (m)

sc-421114mGene KnockoutGFP
1
(0)

IL-6 HDR Plasmid (m)

sc-421114-HDRmHomology Directed RepairPuromycin
1
(0)

IL-6 Double Nickase Plasmid (m)

sc-421114-NICmGene KnockoutPuromycin
1
(0)

IL-6 Double Nickase Plasmid (m2)

sc-421114-NIC-2mGene KnockoutPuromycin
1
(0)

IL-6 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-6 CRISPR Activation Plasmid (h)

sc-400390-ACThGene ActivationPuro, Blast, Hygro
2
(0)

IL-6 CRISPR Activation Plasmid (h2)

sc-400390-ACT-2hGene ActivationPuro, Blast, Hygro
2
(0)

IL-6 Lentiviral Activation Particles (h)

sc-400390-LAChGene ActivationPuro, Blast, Hygro
2
(0)

IL-6 Lentiviral Activation Particles (h2)

sc-400390-LAC-2hGene ActivationPuro, Blast, Hygro
2
(0)

IL-6 CRISPR Activation Plasmid (m)

sc-421114-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

IL-6 CRISPR Activation Plasmid (m2)

sc-421114-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

IL-6 Lentiviral Activation Particles (m)

sc-421114-LACmGene ActivationPuro, Blast, Hygro
1
(0)

IL-6 Lentiviral Activation Particles (m2)

sc-421114-LAC-2mGene ActivationPuro, Blast, Hygro
1
(0)

IL-6 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-6 siRNA (h)

sc-39627hGene SilencingN/A
22
(0)

IL-6 shRNA Plasmid (h)

sc-39627-SHhGene SilencingPuromycin
22
(0)

IL-6 shRNA (h) Lentiviral Particles

sc-39627-VhGene SilencingPuromycin
22
(0)

IL-6 siRNA (m)

sc-39628mGene SilencingN/A
7
(0)

IL-6 shRNA Plasmid (m)

sc-39628-SHmGene SilencingPuromycin
7
(0)

IL-6 shRNA (m) Lentiviral Particles

sc-39628-VmGene SilencingPuromycin
7
(0)

IL-6 siRNA (r)

sc-156148rGene SilencingN/A
1
(0)

IL-6 shRNA Plasmid (h)

sc-156148-SHhGene SilencingPuromycin
1
(0)

IL-6 shRNA (h) Lentiviral Particles

sc-156148-VhGene SilencingPuromycin
1
(0)

IL-6 Transfected Lysates

Empty Table HeaderProduct NameCATALOG #SpeciesCONTROL ANTIBODYCitationsRATING

IL-6 (h2): 293T Lysate

sc-176119h20
(0)