IL-6 Antibody (1): sc-130326
- IL-6 Antibody (1) is a mouse monoclonal IgG2b κ, cited in 88 publications, provided at 200 µg/ml
- raised against recombinant IL-6 of human origin
- IL-6 Antibody (1) is recommended for detection of IL-6 of human origin by WB, IP, IF and IHC(P)
- Anti-IL-6 Antibody (1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for IL-6 Antibody (1) for WB and IHC(P) applications. These reagents are now offered in bundles with IL-6 Antibody (1) (see ordering information below).
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SEE ALSO...
IL-6 Antibody (1) is a mouse monoclonal IgG2b kappa light chain antibody that detects human IL-6 through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-IL-6 antibody (1) is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Interleukin-6, or IL-6, is a multifunctional protein composed of 212 amino acids that plays a pivotal role in immune response, inflammation, and hematopoiesis. IL-6 is primarily secreted by immune cells, such as T cells and macrophages, and is crucial for regulating acute phase response during infection and tissue injury. IL-6′s ability to act as a pro-inflammatory cytokine makes this protein essential for host defense mechanisms, though dysregulation is implicated in various pathological conditions, including autoimmune diseases and cancer. IL-6 exerts effects through a receptor complex that includes an IL-6-specific α chain and a homodimer of the gp130 glycoprotein, leading to JAK/STAT signaling pathway activation, which is vital for transcribing genes involved in inflammation and immune responses. IL-6′s versatility in mediating both protective and pathological processes underscores anti-IL-6 antibody (1)′s importance in research and clinical applications, providing valuable insights into IL-6′s role in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-6 Antibody (1) | sc-130326 | 200 µg/ml | $316.00 | |||
IL-6 Antibody (1): m-IgGκ BP-HRP Bundle | sc-521208 | 200 µg Ab, 40 µg BP | $354.00 | |||
IL-6 Antibody (1): m-IgG2b BP-HRP Bundle | sc-548873 | 200 µg Ab; 10 µg BP | $354.00 | |||
IL-6 Antibody (1) AC | sc-130326 AC | 500 µg/ml, 25% agarose | $416.00 | |||
IL-6 Antibody (1) HRP | sc-130326 HRP | 200 µg/ml | $316.00 | |||
IL-6 Antibody (1) FITC | sc-130326 FITC | 200 µg/ml | $330.00 | |||
IL-6 Antibody (1) PE | sc-130326 PE | 200 µg/ml | $343.00 | |||
IL-6 Antibody (1) Alexa Fluor® 488 | sc-130326 AF488 | 200 µg/ml | $357.00 | |||
IL-6 Antibody (1) Alexa Fluor® 546 | sc-130326 AF546 | 200 µg/ml | $357.00 | |||
IL-6 Antibody (1) Alexa Fluor® 594 | sc-130326 AF594 | 200 µg/ml | $357.00 | |||
IL-6 Antibody (1) Alexa Fluor® 647 | sc-130326 AF647 | 200 µg/ml | $357.00 | |||
IL-6 Antibody (1) Alexa Fluor® 680 | sc-130326 AF680 | 200 µg/ml | $357.00 | |||
IL-6 Antibody (1) Alexa Fluor® 790 | sc-130326 AF790 | 200 µg/ml | $357.00 |