IL-1F7 Activators
IL-1F7 Activators represent a specialized group of chemical compounds that play a pivotal role in the modulation of the biological activity of IL-1F7, a member of the interleukin-1 family involved in immunological and inflammatory processes. These activators are designed to enhance the activity of IL-1F7 through a variety of mechanisms that are tightly regulated and specific to the signaling pathways of this cytokine. The unique property of these activators is to augment the functional activity of IL-1F7 without altering its expression levels or directly binding to the protein itself. Instead, they work by influencing the cellular milieu and the signaling cascades that IL-1F7 is a part of. For instance, certain small molecule agonists might increase the affinity of IL-1F7 for its receptor complex, leading to an increase in downstream signaling efficacy. Other activators may influence the stabilization of the IL-1F7 protein, thereby extending its half-life and sustained signaling within the cellular environment.
Furthermore, some IL-1F7 Activators might function by indirectly enhancing the receptor assembly or by affecting the post-translational modifications of IL-1F7, which are crucial for its activity. These modifications can include the addition or removal of phosphate groups, ubiquitination, and sumoylation, all of which alters the activity state of IL-1F7. Additionally, these activators can modulate the activity of other molecules within the signaling pathway that IL-1F7 is a part of, such as kinases and phosphatases, which in turn can lead to an upregulation of the functional response mediated by IL-1F7. The concerted action of these activators ensures that IL-1F7 can exert its effects more robustly within the context of its involvement in the complex network of immune signaling. This intricate regulation and enhancement of IL-1F7 activity by these chemical activators underscore their significance in the fine-tuning of immunological responses and inflammatory processes at the molecular level.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which in turn can activate PKA. PKA phosphorylation can enhance IL-1F7 activity by facilitating its maturation and secretion. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin modulates the NF-κB pathway, which is involved in inflammatory responses. By inhibiting NF-κB, curcumin can indirectly increase IL-1F7 activity, promoting its anti-inflammatory effects. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol activates SIRT1, an NAD+-dependent deacetylase, which can deacetylate proteins that regulate the NF-κB pathway, potentially enhancing IL-1F7's anti-inflammatory role. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane activates the Nrf2 pathway, which can induce expression of antioxidant response elements. This can indirectly enhance IL-1F7 activity by reducing oxidative stress that may suppress IL-1F7's function. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
Rosiglitazone activates PPARγ, which can interact with NF-κB signaling and may enhance IL-1F7's anti-inflammatory effects by altering the transcriptional regulation of inflammation-related genes. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin inhibits a variety of kinases involved in the inflammatory response, potentially reducing competitive signaling pathways and indirectly enhancing IL-1F7's anti-inflammatory role. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin activates TRPV1, which can lead to the release of neuropeptides that modulate inflammatory responses, potentially enhancing IL-1F7's function in inflammation regulation. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3 modulates immune responses and has been shown to influence the expression of anti-inflammatory cytokines, which could enhance the activity of IL-1F7 by promoting an anti-inflammatory environment. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium affects glycogen synthase kinase-3 (GSK-3) activity, which is involved in NF-κB regulation. By modulating GSK-3, lithium could indirectly augment IL-1F7's anti-inflammatory actions. | ||||||