IL-1F10 inhibitors are a class of chemical compounds that specifically target and inhibit IL-1F10, also known as interleukin-1 family member 10. IL-1F10 belongs to the IL-1 family of cytokines, which play critical roles in modulating immune responses, inflammation, and cellular signaling. IL-1F10 is less well understood than other IL-1 family members like IL-1α and IL-1β, but it is believed to function in immune regulation, particularly by interacting with specific receptors in immune cells. By inhibiting IL-1F10, these compounds block its ability to engage with receptors, thereby disrupting downstream signaling pathways that may regulate immune cell behavior and other cellular processes.
The use of IL-1F10 inhibitors in research enables scientists to investigate the specific biological roles of this cytokine. By inhibiting IL-1F10, researchers can explore how its activity influences immune cell interactions, cytokine production, and immune system regulation. In particular, IL-1F10 inhibitors help uncover its contribution to immune homeostasis and the balance between pro-inflammatory and anti-inflammatory signals. Additionally, the inhibition of IL-1F10 allows for the study of its broader interactions within the IL-1 family and how these interactions affect signaling networks in immune cells. These inhibitors are valuable tools for dissecting the complex dynamics of cytokine signaling and for gaining a deeper understanding of the molecular mechanisms that control immune responses.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Anakinra | 143090-92-0 | sc-507486 | 10 mg | $811.00 | ||
Anakinra is an IL-1 receptor antagonist. By blocking the IL-1 receptor, it can suppress the entire IL-1 pathway, affecting proteins like IL-1F10. | ||||||
Diacerein | 13739-02-1 | sc-204717 sc-204717A | 50 mg 250 mg | $122.00 $555.00 | 2 | |
Diacerein is an anthraquinone derivative that inhibits IL-1β synthesis, impacting the IL-1 pathway and potentially IL-1F10's function. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $81.00 $306.00 | 32 | |
Parthenolide inhibits the activation of NF-κB, a transcription factor downstream of IL-1, thus indirectly influencing IL-1F10. | ||||||
Glycyrrhizic acid | 1405-86-3 | sc-279186 sc-279186A | 1 g 25 g | $57.00 $333.00 | 7 | |
Glycyrrhizin can inhibit IL-1β-induced inflammation. This suppression might affect the broader IL-1 pathway, including IL-1F10. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
Bay 11-7082 inhibits the activation of NF-κB, which can reduce IL-1-mediated inflammation and possibly impact IL-1F10's function. | ||||||
Pyrrolidinedithiocarbamic acid ammonium salt | 5108-96-3 | sc-203224 sc-203224A | 5 g 25 g | $33.00 $64.00 | 11 | |
PDTC acts as an NF-κB inhibitor. By inhibiting this transcription factor, it might indirectly modulate IL-1F10 activity. | ||||||
SC514 | 354812-17-2 | sc-205504 sc-205504A | 5 mg 10 mg | $67.00 $91.00 | 13 | |
SC-514 is an IKK-2 inhibitor that blocks NF-κB activation. By inhibiting NF-κB, it might indirectly affect IL-1F10's function. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Triptolide has anti-inflammatory properties and can inhibit the NF-κB pathway, potentially influencing IL-1F10 indirectly. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid, has been shown to inhibit IL-1 mediated responses, which can indirectly affect IL-1F10's signaling. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
Apigenin inhibits IL-1β expression and may have an indirect impact on IL-1F10 activity. | ||||||