IFN-α16 Inhibitors
IFN-α16 inhibitors constitute a specialized class of chemical compounds designed to selectively target and modulate the function of Interferon-alpha 16 (IFN-α16). Interferons, as a family of signaling proteins, play a pivotal role in orchestrating the immune response to viral infections and other challenges. IFN-α16, a specific subtype within the interferon-alpha family, is distinguished by its unique molecular structure and functional characteristics. The inhibitors tailored for IFN-α16 are meticulously crafted to interact with specific binding sites on the protein, aiming to disrupt its normal interactions within the cellular environment and potentially influence immune signaling pathways.
The molecular architecture of IFN-α16 inhibitors is precisely engineered to engage with distinct regions of the protein, inducing changes in its conformation and dynamics. This interaction holds the potential to impact the protein's ability to transmit signals associated with antiviral defenses. In laboratory research, these inhibitors serve as essential tools, enabling scientists to delve into the nuanced functions of IFN-α16 in immune responses and contributing to a deeper understanding of the intricate interplay within the immune system. By manipulating the function of IFN-α16, researchers seek to unravel the complex mechanisms of immune signaling, shedding light on the broader implications for cellular function and the orchestration of immune defenses against viral pathogens. The study of IFN-α16 inhibitors stands at the forefront of advancing our comprehension of immune system dynamics and the finely tuned regulation of antiviral responses within the complex network of the immune system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
NFκB Activation Inhibitor II, JSH-23 | 749886-87-1 | sc-222061 sc-222061C sc-222061A sc-222061B | 5 mg 10 mg 50 mg 100 mg | $214.00 $257.00 $1775.00 $2003.00 | 34 | |
An inhibitor of NF-κB nuclear translocation, which may decrease IFN-α16 expression by limiting transcription factor activity. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
A proteasome inhibitor that can prevent IκB degradation, thereby inhibiting NF-κB and possibly reducing IFN-α16 expression. | ||||||
NMS-873 | 1418013-75-8 | sc-478803 | 5 mg | $300.00 | ||
Specifically inhibits IKK-β, which is involved in the activation of NF-κB, potentially decreasing the expression of IFN-α16. | ||||||
NFκB Inhibitor | 213546-53-3 | sc-3060 sc-3060B sc-3060A | 0.5 mg 10 mg 5 mg | $169.00 $1294.00 $743.00 | 69 | |
A cell-permeable peptide that inhibits NF-κB translocation to the nucleus, potentially suppressing IFN-α16 production. | ||||||
BAY 11-7085 | 196309-76-9 | sc-202490 sc-202490A | 10 mg 50 mg | $124.00 $526.00 | 55 | |
Inhibits NF-κB by blocking phosphorylation of IκB-α, which could reduce IFN-α16 levels. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $81.00 $306.00 | 32 | |
A sesquiterpene lactone that can inhibit NF-κB activation, possibly impacting IFN-α16 expression. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
A selective inhibitor of MEK, which could reduce the activation of downstream transcription factors involved in IFN-α16 expression. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A p38 MAPK inhibitor which might suppress IFN-α16 production by altering the response to stress signals. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor, which could affect the AKT signaling pathway and potentially decrease IFN-α16 expression. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor that may lead to reduced IFN-α16 expression by impacting various downstream signaling events. | ||||||