Humanin Activators
Humanin is a small peptide encoded by the mitochondrial genome that has garnered significant attention in the field of molecular biology and aging research. Discovered in the early 2000s, Humanin was initially identified for its role in protecting cells from programmed cell death or apoptosis, particularly in the context of neurodegenerative diseases and age-related disorders.
Humanin's primary function is to counteract the pro-apoptotic effects of certain cell death pathways, making it a factor in promoting cell survival. This peptide exerts its anti-apoptotic effects by interacting with various cellular signaling pathways, including those related to oxidative stress and inflammation. By inhibiting apoptosis, Humanin may contribute to the maintenance of tissue homeostasis and play a protective role against neurodegenerative conditions like Alzheimer's disease and Parkinson's disease.Moreover, Humanin has also been implicated in broader aspects of health and longevity. Some studies suggest that elevated levels of Humanin may be associated with increased lifespan and improved metabolic health. Additionally, research is ongoing to explore the applications of Humanin in age-related diseases and conditions beyond neurodegeneration, such as diabetes and cardiovascular disease.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Metformin, a biguanide, may enhance Humanin expression indirectly through AMPK activation, which is linked to mitochondrial biogenesis and stress response. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, a polyphenol, might upregulate Humanin expression by activating SIRT1, a regulator of mitochondrial function and cellular stress response. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can potentially increase Humanin levels by modulating oxidative stress pathways and enhancing mitochondrial function. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane, found in cruciferous vegetables, could induce Humanin expression by activating Nrf2, a key regulator of cellular antioxidant response. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a catechin in green tea, may influence Humanin expression through its antioxidant properties and modulation of cellular stress pathways. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid, potentially enhances Humanin expression by modulating oxidative stress and inflammation pathways. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine may upregulate Humanin indirectly through its effects on AMPK activation and mitochondrial function. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
Alpha-lipoic acid, an antioxidant, could influence Humanin expression through its role in cellular metabolism and oxidative stress response. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
Nicotinamide riboside, a form of vitamin B3, may affect Humanin expression by enhancing NAD+ levels and sirtuin activity, impacting mitochondrial health. | ||||||
Pterostilbene, Pterocarpus marsupium | 537-42-8 | sc-203223 sc-203223A | 10 mg 100 mg | $211.00 $1196.00 | ||
Pterostilbene, similar to resveratrol, might influence Humanin expression through sirtuin activation and modulation of oxidative stress. | ||||||