The classification of HSV-2 gD Activators refers to a group of chemical compounds that can indirectly influence the activity or expression of glycoprotein D of Herpes Simplex Virus type 2. These activators do not interact directly with the viral protein. Instead, they exert their influence through modulation of host cellular processes, signaling pathways, and immune responses that are crucial in the life cycle of the virus and the function of gD.
The primary mechanisms through which these chemicals exert their influence involve modulation of immune response, alteration of gene expression, and impact on cellular signaling pathways. For instance, compounds like Curcumin, Resveratrol, and EGCG are known to affect NF-kB signaling and other pathways involved in inflammatory responses. Such modulation can have downstream effects on the immune system's ability to respond to viral infections, potentially influencing the activity or expression of viral proteins like HSV-2 gD.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Modulates NF-kB signaling, potentially influencing immune response mechanisms that could affect the activity or expression of HSV-2 gD. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Impacts SIRT1 activation and NF-kB pathway, potentially modulating immune responses and indirectly influencing HSV-2 gD. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Affects various signaling pathways including those involved in inflammatory responses, which may indirectly impact HSV-2 gD activity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Influences cellular signaling pathways, including tyrosine kinase inhibitors, which may have an indirect effect on HSV-2 gD activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Modulates cellular signaling and has anti-inflammatory properties, potentially influencing pathways related to HSV-2 gD. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Histone deacetylase inhibitor, potentially affecting gene expression patterns that could indirectly influence HSV-2 gD activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Increases cAMP levels, potentially influencing signaling pathways that could indirectly impact HSV-2 gD activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Inhibits GSK-3, potentially affecting signaling pathways related to viral replication and HSV-2 gD expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Modulates gene expression, potentially influencing immune response and indirectly HSV-2 gD activity. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
A corticosteroid that modulates inflammation and immune response, potentially influencing HSV-2 gD. | ||||||