Date published: 2026-2-11

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HSV-2 gD Activators

The classification of HSV-2 gD Activators refers to a group of chemical compounds that can indirectly influence the activity or expression of glycoprotein D of Herpes Simplex Virus type 2. These activators do not interact directly with the viral protein. Instead, they exert their influence through modulation of host cellular processes, signaling pathways, and immune responses that are crucial in the life cycle of the virus and the function of gD.

The primary mechanisms through which these chemicals exert their influence involve modulation of immune response, alteration of gene expression, and impact on cellular signaling pathways. For instance, compounds like Curcumin, Resveratrol, and EGCG are known to affect NF-kB signaling and other pathways involved in inflammatory responses. Such modulation can have downstream effects on the immune system's ability to respond to viral infections, potentially influencing the activity or expression of viral proteins like HSV-2 gD.

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Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Modulates NF-kB signaling, potentially influencing immune response mechanisms that could affect the activity or expression of HSV-2 gD.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Impacts SIRT1 activation and NF-kB pathway, potentially modulating immune responses and indirectly influencing HSV-2 gD.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

Affects various signaling pathways including those involved in inflammatory responses, which may indirectly impact HSV-2 gD activity.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Influences cellular signaling pathways, including tyrosine kinase inhibitors, which may have an indirect effect on HSV-2 gD activity.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Modulates cellular signaling and has anti-inflammatory properties, potentially influencing pathways related to HSV-2 gD.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Histone deacetylase inhibitor, potentially affecting gene expression patterns that could indirectly influence HSV-2 gD activity.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Increases cAMP levels, potentially influencing signaling pathways that could indirectly impact HSV-2 gD activity.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Inhibits GSK-3, potentially affecting signaling pathways related to viral replication and HSV-2 gD expression.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Modulates gene expression, potentially influencing immune response and indirectly HSV-2 gD activity.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

A corticosteroid that modulates inflammation and immune response, potentially influencing HSV-2 gD.