HoxC12, also known as Homeobox C12, is a protein that is encoded by the HOXC12 gene in humans. This protein belongs to the highly conserved Hox gene family, which plays a crucial role in body patterning during embryonic development.Hox proteins are characterized by a 60-amino acid homeodomain, a DNA-binding domain, enabling these proteins to function as transcription factors. They can turn genes on or off, thereby directing the formation of specific body structures along the anterior-posterior axis (head-tail direction) of organisms.
Specifically, HoxC12 is part of the 'C' cluster of Hox genes. In vertebrates, there are four clusters (A, B, C, and D) arranged on different chromosomes. Each cluster contains several Hox genes that are expressed in a spatially and temporally controlled manner during embryonic development.The exact role of HoxC12 remains to be fully elucidated, but like other Hox genes, it's likely involved in directing the formation of specific body structures during development. The expression of HoxC12, like other Hox genes, follows a principle known as colinearity, where its position within the HOXC cluster corresponds to the timing and location of its expression along the body axis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Can modulate gene expression, potentially affecting HOXC12 through transcriptional regulation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, can alter gene expression patterns, possibly impacting HOXC12. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor, could impact gene expression and indirectly influence HOXC12. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol that can modulate various signaling pathways, potentially influencing HOXC12 activity or expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Known for its effect on transcription factors and signaling pathways, potentially influencing HOXC12. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Affects gene expression and has been shown to interact with various transcription factors, possibly affecting HOXC12. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A histone deacetylase inhibitor, potentially impacting HOXC12 expression by altering chromatin structure. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, potentially impacting HOXC12 expression through cAMP-dependent pathways. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences Wnt signaling and glycogen synthase kinase 3 (GSK-3) activity, potentially affecting HOXC12. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor, potentially affecting pathways that could influence HOXC12 activity or expression. | ||||||