HIV-1 Gag Inhibitors
HIV-1 Gag inhibitors belong to a specific class of compounds designed to target a crucial protein in the human immunodeficiency virus type 1 (HIV-1) lifecycle known as the Gag polyprotein. This polyprotein plays a pivotal role in the assembly and release of new viral particles from infected host cells. Inhibitors of HIV-1 Gag function by disrupting various stages of viral replication, particularly the assembly and budding of viral particles, which are essential for the virus's ability to spread within the host. These inhibitors are part of a broader category of antiretroviral drugs developed to combat HIV-1 infection, and they contribute significantly to the arsenal of agents used in managing the disease.
HIV-1 Gag inhibitors encompass a diverse array of compounds, including small molecules and peptides, which interfere with the proper processing and function of the Gag polyprotein. By targeting Gag, these inhibitors impede the virus's ability to form mature and infectious viral particles. Some of these compounds work by disrupting the assembly of the viral capsid, while others interfere with the release of virions from the host cell membrane. Overall, HIV-1 Gag inhibitors represent a promising avenue of research in the ongoing battle against HIV/AIDS, as they offer strategies to hinder viral replication and transmission. Further exploration and refinement of these compounds may hold the key to advancing our understanding of HIV-1 biology and in developing novel approaches to combat this devastating viral infection.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, a natural polyphenolic compound found in turmeric, has demonstrated potential in modulating various cellular processes. It may interfere with the HIV-1 life cycle, potentially influencing the expression of the Gag protein. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a natural compound found in grapes, has shown antioxidant and anti-inflammatory properties. It may impact viral replication and influence the expression of viral proteins, including Gag. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, a flavonoid found in many plants, exhibits antioxidant properties. It may play a role in modulating cellular pathways, potentially affecting the expression of the HIV-1 Gag protein. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, a major component of green tea, has demonstrated antioxidant and anti-inflammatory effects. It may influence viral replication and the expression of HIV-1 proteins, including Gag. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane, found in cruciferous vegetables, has shown potential in modulating cellular pathways and antioxidant responses. It may impact the expression of viral proteins, including the Gag protein of HIV-1. | ||||||
Silymarin group, mixture of isomers | 65666-07-1 | sc-301806 | 50 g | $319.00 | ||
Silymarin, found in milk thistle, has hepatoprotective and antioxidant properties. It may play a role in influencing viral replication and the expression of HIV-1 proteins, including Gag. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Berberine, an alkaloid found in various plants, has demonstrated various biological activities. It may affect cellular pathways, potentially influencing the expression of the HIV-1 Gag protein. | ||||||
Baicalein | 491-67-8 | sc-200494 sc-200494A sc-200494B sc-200494C | 10 mg 100 mg 500 mg 1 g | $31.00 $41.00 $159.00 $286.00 | 12 | |
Baicalein, a flavonoid found in the roots of Scutellaria baicalensis, exhibits anti-inflammatory and antioxidant properties. It may impact the expression of HIV-1 proteins, including Gag. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, an isoflavone found in soybeans, has shown potential in modulating cellular signaling pathways. It may influence the expression of the HIV-1 Gag protein. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $57.00 $93.00 $240.00 $713.00 | 8 | |
Ellagic acid, found in various fruits and nuts, has antioxidant properties. It may play a role in modulating cellular responses and potentially affect the expression of the HIV-1 Gag protein. | ||||||