Histone cluster 2 H3C Inhibitors
Histone cluster 2 H3C inhibitors represent a specialized chemical class engineered to selectively target and modulate the function of H3C histone proteins. H3C, a variant within the histone cluster 2 family, plays a fundamental role in orchestrating chromatin architecture and gene regulation. As an integral component of nucleosomes, H3C contributes to the compact packaging of DNA, exerting influence over the intricate dynamics of gene expression. The inhibitors developed for Histone cluster 2 H3C are intricately designed to interact with the unique molecular structure of this histone variant, aiming to perturb its normal interactions within the nucleosome and potentially reshape the chromatin landscape.
The molecular architecture of Histone cluster 2 H3C inhibitors is tailored for precision, strategically engaging specific binding sites on H3C to induce alterations in its conformation and dynamics. This interaction holds the promise of impacting the accessibility of DNA, thereby influencing the regulatory processes governing gene expression. In laboratory investigations, researchers employ these inhibitors as invaluable tools to unravel the nuanced roles of H3C in diverse cellular processes, contributing to a deeper understanding of chromatin biology. By manipulating the function of H3C, scientists seek to unveil the intricate mechanisms of gene regulation, shedding light on the broader implications of epigenetic processes for cellular function and development. The exploration of Histone cluster 2 H3C inhibitors stands at the forefront of advancing our understanding of chromatin dynamics and the finely tuned orchestration of gene expression within the cellular milieu.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, disrupting RNA synthesis. This interference with transcription may impede the expression of H3 clustered histone 14. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $196.00 | 9 | |
Panobinostat is a histone deacetylase inhibitor, altering chromatin structure. By inhibiting histone deacetylation, it may interfere with the transcriptional regulation of H3 clustered histone 14. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor, modifying DNA methylation patterns. Changes in methylation status can influence gene expression, potentially affecting the transcription of H3 clustered histone 14. | ||||||
Daunorubicin hydrochloride | 23541-50-6 | sc-200921 sc-200921A sc-200921B sc-200921C | 10 mg 50 mg 250 mg 1 g | $103.00 $429.00 $821.00 $1538.00 | 4 | |
Daunorubicin intercalates into DNA and inhibits topoisomerase II. This dual action can disrupt transcription and induce DNA damage responses, potentially impacting the expression of H3 clustered histone 14. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Nicotinamide (NAM) acts as a histone deacetylase inhibitor. Its ability to influence chromatin structure may interfere with the transcriptional regulation of H3 clustered histone 14. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
Cisplatin forms DNA adducts, inducing DNA damage. This damage response can affect transcription, potentially influencing the expression of H3 clustered histone 14. | ||||||
Tris Buffered Saline: 1 L of 1X | sc-362185 | 1 L | $20.00 | 3 | ||
Tubacin is a histone deacetylase 6 (HDAC6) inhibitor. By specifically targeting HDAC6, it may modulate the acetylation status of non-histone proteins, potentially impacting the expression of H3 clustered histone 14. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Decitabine is a DNA methyltransferase inhibitor, altering DNA methylation patterns. Changes in methylation status can influence gene expression, potentially affecting the transcription of H3 clustered histone 14. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $57.00 $93.00 $240.00 $713.00 | 8 | |
Ellagic acid exhibits antioxidant properties and may influence transcription factors. Its interaction with these factors may impact the expression of H3 clustered histone 14. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Camptothecin inhibits topoisomerase I, inducing DNA damage. This damage response can disrupt transcription, potentially influencing the expression of H3 clustered histone 14. | ||||||