Histone cluster 1 H2AO Inhibitors
Histone cluster 1 H2AO inhibitors form a specific class of chemical compounds meticulously designed to modulate the activity of histone cluster 1 H2AO proteins. H2AO, also known as H2A histone family member O, is part of the histone family of proteins found in humans and various organisms. Histones are critical components of chromatin, the complex structure that packages and organizes DNA in the cell nucleus. Chromatin plays a central role in regulating gene expression, DNA replication, and genome stability. H2AO, as a subtype of histone H2A, contributes to the dynamic and intricate process of chromatin remodeling and gene regulation.
H2AO inhibitors typically consist of small molecules or chemical compounds that are specifically engineered to bind to H2AO proteins, targeting either their active sites or allosteric sites. This interaction can lead to the modulation of H2AO's behavior, potentially impacting its role in chromatin structure, gene expression, and DNA packaging. Researchers in the fields of molecular biology and pharmacology are dedicated to unraveling the molecular mechanisms and functions of histone cluster 1 H2AO proteins within the context of chromatin dynamics, aiming to gain insights into the complex processes that govern epigenetic regulation and genomic stability. The development of H2AO inhibitors represents an ongoing and dynamic area of research, contributing significantly to our understanding of chromatin biology and its critical role in gene expression and various cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A nucleoside analog that incorporates into DNA and RNA, potentially affecting DNA methylation and gene expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
Similar to 5-azacytidine, it can inhibit DNA methyltransferase, leading to hypomethylation and altered gene expression. | ||||||
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $129.00 $284.00 $1004.00 | 3 | |
A cytidine analog that can trap DNA methyltransferases, potentially affecting DNA methylation and gene expression. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
A non-nucleoside DNA methyltransferase inhibitor, potentially altering gene expression patterns. | ||||||
Fostriecin | 87860-39-7 | sc-202160 | 50 µg | $265.00 | 9 | |
A phosphatase inhibitor that may alter signaling pathways affecting gene expression and cell cycle progression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
An HDAC inhibitor that can induce hyperacetylation of histones, leading to changes in gene expression. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
A synthetic benzamide derivative that acts as an HDAC inhibitor, affecting chromatin structure and gene expression. | ||||||
Scriptaid | 287383-59-9 | sc-202807 sc-202807A | 1 mg 5 mg | $64.00 $183.00 | 11 | |
An HDAC inhibitor with potential to alter acetylation patterns on histones and affect gene expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another HDAC inhibitor that can change the acetylation state of histones, potentially affecting transcription. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $200.00 | 9 | |
A pan-HDAC inhibitor that can broadly affect gene expression by changing the acetylation state of histones. | ||||||