Date published: 2026-4-24

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HGFL α Activators

HGFL α activators belong to a distinctive chemical class characterized by their unique ability to modulate the activity of Hepatocyte Growth Factor-like Protein α (HGFL α). This class of compounds typically interacts with specific receptors or signaling pathways associated with HGFL α, a protein that plays a pivotal role in various cellular processes, including cell growth, differentiation, and migration. Structurally, HGFL α activators exhibit a diverse range of chemical architectures, allowing for intricate interactions with the target protein. These compounds often feature functional groups or moieties that facilitate binding to the active sites of HGFL α or its associated receptors, triggering downstream cellular responses.

The mechanism of action of HGFL α activators involves the modulation of signaling cascades implicated in cellular development and tissue homeostasis. By selectively engaging with components of the HGFL α pathway, these activators exert control over cellular functions, influencing processes such as cell proliferation and tissue repair. Researchers have been keenly exploring the structural variations within this chemical class to elucidate the precise molecular interactions that underlie their activity. Additionally, the study of HGFL α activators holds promise for advancing our understanding of the intricate regulatory networks governing cell behavior and may provide valuable insights into the broader field of cell biology. Ongoing research efforts aim to further characterize the pharmacological properties and biological implications of HGFL α activators, shedding light on their applications in various scientific contexts.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

D-erythro-Sphingosine-1-phosphate

26993-30-6sc-201383
sc-201383D
sc-201383A
sc-201383B
sc-201383C
1 mg
2 mg
5 mg
10 mg
25 mg
$165.00
$322.00
$570.00
$907.00
$1727.00
7
(1)

Sphingosine 1-phosphate (S1P) binds to its receptors, initiating a signaling cascade that can lead to the activation of MST1 kinase and subsequently HGFL α. This enhances HGFL α's involvement in angiogenesis and cellular migration.

Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3)

10417-94-4sc-200766
sc-200766A
100 mg
1 g
$104.00
$431.00
(0)

Eicosapentaenoic acid (EPA) can lead to the activation of MST1 through its metabolites, which modulate inflammatory pathways where MST1 and HGFL α are implicated, thus enhancing HGFL α's anti-inflammatory responses.

Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3)

6217-54-5sc-200768
sc-200768A
sc-200768B
sc-200768C
sc-200768D
100 mg
1 g
10 g
50 g
100 g
$94.00
$210.00
$1779.00
$8021.00
$16657.00
11
(1)

Docosahexaenoic acid (DHA) affects membrane fluidity and can activate signaling pathways involving MST1 kinase, leading to the functional enhancement of HGFL α in neuronal development and cognitive function.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin elevates intracellular cAMP levels, which can potentiate the MST1 signaling pathway, leading to the activation of HGFL α and promoting its role in cell cycle regulation.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

LY294002 inhibits the PI3K/Akt pathway, which can lead to the activation of MST1 kinase, and consequently, the enhancement of HGFL α signaling involved in apoptosis and cell growth.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol activates SIRT1, which can deacetylate and activate MST1 kinase. Through the activation of MST1, HGFL α's functional activity in cell survival and metabolism is enhanced.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin can inhibit NF-κB, which leads to the activation of MST1 kinase. This activation enhances the functional role of HGFL α in the cellular stress response and inflammation resolution.