HEXA Inhibitors
Items 1 to 10 of 13 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(Z)-Pugnac | 132489-69-1 | sc-204415A sc-204415 | 5 mg 10 mg | $220.00 $373.00 | 3 | |
(Z)-Pugnac is a versatile acid halide characterized by its unique reactivity and ability to form stable intermediates in nucleophilic acyl substitution reactions. Its distinct stereochemistry influences the orientation of electrophilic attack, enhancing selectivity in synthetic pathways. The compound exhibits strong dipole interactions, which facilitate solvation and enhance reactivity with various nucleophiles. Additionally, (Z)-Pugnac's ability to stabilize transition states contributes to its efficient reaction kinetics, making it a valuable tool in organic synthesis. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine is a lysosomotropic agent, which can increase lysosomal pH and thereby impede the function of lysosomal enzymes like HEXA. | ||||||
Galacto-PUGNAc | 1145878-98-3 | sc-489532 sc-489532A | 0.5 mg 5 mg | $666.00 $5200.00 | ||
Galacto-PUGNAc is a distinctive acid halide known for its selective reactivity in glycosylation reactions. Its unique structural features promote specific interactions with carbohydrate moieties, allowing for the formation of complex glycosidic bonds. The compound's steric hindrance influences the regioselectivity of nucleophilic attacks, while its polar functional groups enhance solubility in various solvents. This combination of properties leads to efficient reaction pathways and robust intermediates in synthetic applications. | ||||||
hydroxychloroquine | 118-42-3 | sc-507426 | 5 g | $56.00 | 1 | |
Hydroxychloroquine, like chloroquine, also acts by increasing lysosomal pH, thus indirectly inhibiting HEXA's function. | ||||||
Propranolol | 525-66-6 | sc-507425 | 100 mg | $180.00 | ||
Propranolol, a beta-adrenergic antagonist, can influence the cellular trafficking of lysosomal enzymes, potentially affecting HEXA activity. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $367.00 | ||
Verapamil, a calcium channel blocker, can alter intracellular calcium concentrations, which can indirectly influence the function of lysosomal enzymes like HEXA. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine disrupts microtubule function, which could impact the trafficking of HEXA to the lysosome. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole, like colchicine, disrupts microtubules, potentially affecting the cellular localization of HEXA. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Monensin is a sodium ionophore that can disrupt protein trafficking to lysosomes, which may indirectly influence HEXA activity. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
Bafilomycin A1 inhibits vacuolar-type H+-ATPase, thereby increasing lysosomal pH and indirectly inhibiting HEXA's function. | ||||||